2-Keto palmitic acid

Base Information

• Chemical Name: 2-Keto palmitic acid
• CAS No.: 2570-24-3
• Molecular Formula: C16H30O3
• Molecular Weight: 270.412
• DSSTox Substance ID: DTXSID10415262
• Nikkaji Number: J206.172D
• Wikidata: Q27159313
• Metabolomics Workbench ID: 1573
• Mol file: 2570-24-3.mol

Synonyms:2-keto palmitic acid;2-oxohexadecanoic acid;2-oxo-hexadecanoic acid;2-oxopalmitic acid;2-ketopalmitic acid;2oxo-PALM;2570-24-3;2-ketohexadecanoic acid;SCHEMBL338260;CHEBI:86988;DTXSID10415262;LMFA01060050;Q27159313

Chemical Property of 2-Keto palmitic acid

Chemical Property:

• XLogP3: 6.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 270.21949481
• Heavy Atom Count: 19
• Complexity: 236

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCC(=O)C(=O)O

Technology Process of 2-Keto palmitic acid

There total 7 articles about 2-Keto palmitic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

methyl 4-oxo-trans-2-octadecenoate (21436-53-3) → palmitic acid (1002-84-2) + 2-oxo-hexadecanoic acid (2570-24-3) + methyl 3-chloro-2-nitroso-4-oxooctadecanoate (103897-33-2) + methyl 3-hydroxy-2-oximino-4-oxooctadecanoate (103897-36-5)

Guidance literature:

With nitrosylchloride; In dichloromethane; for 50h; Further byproducts given; Ambient temperature;

Reference yield: 15.0%

methyl 4-oxo-trans-2-octadecenoate (21436-53-3) → palmitic acid (1002-84-2) + 2-oxo-hexadecanoic acid (2570-24-3) + methyl 2-chloro-3-nitroso-4-oxooctadecanoate (103897-34-3) + methyl 2-hydroxy-3-oximino-4-oxooctadecanoate (103897-35-4)

Guidance literature:

With nitrosylchloride; In dichloromethane; for 50h; Further byproducts given; Ambient temperature;

Reference yield: 12.0%

methyl 4-oxo-trans-2-octadecenoate (21436-53-3) → palmitic acid (1002-84-2) + 2-oxo-hexadecanoic acid (2570-24-3) + methyl 3-azido-2-iodo-4-oxooctadecanoate + methyl 2-azido-3-hydroxy-4-oxooctadecanoate

Guidance literature:

With iodine(I) azide; In acetonitrile; for 72h; Further byproducts given; Ambient temperature;

upstream raw materials:

methyl 4-oxo-trans-2-octadecenoate

1-hexadecylcarboxylic acid

Downstream raw materials:

palmitic acid

2-oxohexadecanoic acid 2,4,6-tri-iso-propylbenzenesulphonylhydrazone

Refernces

• 1、 Khan, Mushfiquddin,Ahmad, Suhail,Ahmad, M. S.,Osman, S. M.. "Nitrosochlorination and Azidoiodination of Methyl 4-Oxo-trans-2-octadecenoate". . p. 1043 - 1046. Retrieved 2007/10/02.