3,3,3-Triphenylpropionic acid

Base Information

• Chemical Name: 3,3,3-Triphenylpropionic acid
• CAS No.: 900-91-4
• Molecular Formula: C21H18O2
• Molecular Weight: 302.373
• Hs Code.: 29163990
• Mol file: 900-91-4.mol

Synonyms:Propionicacid, 3,3,3-triphenyl- (6CI,7CI,8CI);3,3,3-Triphenylpropanoic acid;3,3,3-Triphenylpropionic acid;NSC 131292;

Chemical Property of 3,3,3-Triphenylpropionic acid

Chemical Property:

• Appearance/Colour: WHITE TO SLIGHTLY YELLOW CRYSTALLINE POWDER
• Vapor Pressure: 2.75E-08mmHg at 25°C
• Melting Point: 179-183 °C
• Boiling Point: 433.6 °C at 760 mmHg
• PKA: 4.25±0.10(Predicted)
• Flash Point: 330.3 °C
• PSA: 37.30000
• Density: 1.161 g/cm³
• LogP: 4.49570
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,3,3-Triphenylpropionic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26-37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 3,3,3-Triphenylpropionic acid is used as pharmaceutical intermediates.

Technology Process of 3,3,3-Triphenylpropionic acid

There total 23 articles about 3,3,3-Triphenylpropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

triphenylmethyl alcohol (76-84-6) → 3,3,3-triphenylpropionic acid (900-91-4) + 3,3,3-triphenylpropionyl chloride (33166-49-3)

Guidance literature:

With malonic acid; In ethanol;

Reference yield:

triphenylmethyl alcohol (76-84-6) → 3,3,3-triphenylpropionic acid (900-91-4)

Guidance literature:

With malonic acid;

Reference yield:

3,3,3-triphenylpropionyl chloride (33166-49-3) → 3,3,3-triphenylpropionic acid (900-91-4)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01202a031

upstream raw materials:

tetrachloromethane

1,1,1,6,6,6-hexaphenyl-hex-3-ene

triphenylmethyl alcohol

malonic acid

Downstream raw materials:

ethyl 3,3,3-triphenylpropionate

3,3,3-triphenylpropionyl chloride

3,3-diphenyl-indan-1-one

3,3,3-tris-(4-nitro-phenyl)-propionic acid

Refernces

• 1、 -. "Amphiphilic agents for membrane protein solubilization". . . Retrieved 2008/06/13.
• 2、 -. "1-(3,3,3-Triarylalkyl)-4-phenyl-piperidinealkanols". . . Retrieved 2008/06/13.