3t-(5-chloro-[2]furyl)-acrylic acid

Base Information

• Chemical Name: 3t-(5-chloro-[2]furyl)-acrylic acid
• CAS No.: 111252-98-3
• Molecular Formula: C₇H₅ClO₃
• Molecular Weight: 172.568
• Mol file: 111252-98-3.mol

Synonyms:

Chemical Property of 3t-(5-chloro-[2]furyl)-acrylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3t-(5-chloro-[2]furyl)-acrylic acid

There total 4 articles about 3t-(5-chloro-[2]furyl)-acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-2-furaldehyde (21508-19-0) + acetic anhydride (108-24-7) → 3t-(5-chloro-[2]furyl)-acrylic acid (111252-98-3,75426-52-7)

Guidance literature:

With potassium acetate; at 140 ℃;

Reference yield:

5-chlorofuran-2-carboxylic acid (618-30-4) → 3t-(5-chloro-[2]furyl)-acrylic acid (111252-98-3,75426-52-7)

Guidance literature:

Multi-step reaction with 3 steps

1: benzene; thionyl chloride

2: palladium/barium sulfate; xylene / 140 °C / Hydrogenation

3: pyridine

With pyridine; Pd-BaSO₄; thionyl chloride; xylene; benzene;

Reference yield:

5-chlorofuran-2-carbonyl chloride (24078-79-3) → 3t-(5-chloro-[2]furyl)-acrylic acid (111252-98-3,75426-52-7)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium/barium sulfate; xylene / 140 °C / Hydrogenation

2: pyridine

With pyridine; Pd-BaSO₄; xylene;

upstream raw materials:

5-chloro-2-furaldehyde

malonic acid

acetic anhydride

5-chlorofuran-2-carboxylic acid