6'-DesMethyl-6'-carboxy Etoricoxib

Base Information

• Chemical Name: 6'-DesMethyl-6'-carboxy Etoricoxib
• CAS No.: 349536-39-6
• Molecular Formula: C₁₈H₁₃ClN₂O₄S
• Molecular Weight: 388.831
• Mol file: 349536-39-6.mol

Synonyms:

Chemical Property of 6'-DesMethyl-6'-carboxy Etoricoxib

Chemical Property:

• Boiling Point: 598.8±50.0 °C(Predicted)
• PKA: 3.24±0.10(Predicted)
• Density: 1.425±0.06 g/cm3(Predicted)

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

6’-Desmethyl-6’-carboxyEtoricoxib ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 6’-Desmethyl-6’-carboxy Etoricoxib is a derivative of Etoricoxib (E934100),a selective cyclo-oxygenase-2 (COX-2) inhibitor that is used to improve the signs and symptoms of osteoarthritis and rheumatoid arthritis.

Technology Process of 6'-DesMethyl-6'-carboxy Etoricoxib

There total 1 articles about 6'-DesMethyl-6'-carboxy Etoricoxib which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

etoricoxib (202409-33-4) → 6'-Carboxyetoricoxib (349536-39-6)

Guidance literature:

With potassium permanganate; In water; tert-butyl alcohol; at 90 ℃; for 15h;

DOI:10.1016/S0960-894X(01)00135-4

upstream raw materials:

etoricoxib

Refernces