rac-threo-3-Hydroxyleucin-N-sulfamat Natriumsalz

Base Information

• Chemical Name: rac-threo-3-Hydroxyleucin-N-sulfamat Natriumsalz
• CAS No.: 133071-07-5
• Molecular Formula: C₆H₁₂NO₆S*Na
• Molecular Weight: 249.22
• Mol file: 133071-07-5.mol

Synonyms:

Chemical Property of rac-threo-3-Hydroxyleucin-N-sulfamat Natriumsalz

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-threo-3-Hydroxyleucin-N-sulfamat Natriumsalz

There total 4 articles about rac-threo-3-Hydroxyleucin-N-sulfamat Natriumsalz which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

(2RS,3RS)-2-amino-3-hydroxy-4-methylpentanoic acid (5817-22-1,6645-45-0,10148-70-6,10148-71-7,28908-11-4,35016-54-7,35016-62-7,87421-23-6,87421-24-7) → rac-threo-3-Hydroxyleucin-N-sulfamat Natriumsalz (133071-07-5,133071-08-6)

Guidance literature:

With sulfur trioxide pyridine complex; potassium carbonate; In water;

Reference yield: 65.0%

D,L-erythro β-Hydroxyleucine (5817-22-1,6645-45-0,10148-70-6,10148-71-7,28908-11-4,35016-54-7,35016-62-7,87421-23-6,87421-24-7) → rac-erythro-3-Hydroxyleucin-N-sulfamat Natriumsalz (133071-07-5,133071-08-6)

Guidance literature:

With sulfur trioxide pyridine complex; potassium carbonate; In water;

Reference yield:

(2RS,3RS)-2-amino-3-hydroxy-4-methylpentanoic acid (5817-22-1,6645-45-0,10148-70-6,10148-71-7,28908-11-4,35016-54-7,35016-62-7,87421-23-6,87421-24-7) → rac-erythro-3-Hydroxyleucin-N-sulfamat Natriumsalz (133071-07-5,133071-08-6)

Guidance literature:

Multi-step reaction with 3 steps

2: 2N HCl / acetone / Heating

3: 65 percent / K₂CO₃, pyridine-SO₃-complex / H₂O

With hydrogenchloride; sulfur trioxide pyridine complex; potassium carbonate; In water; acetone;

upstream raw materials:

D,L-erythro β-Hydroxyleucine

(2RS,3RS)-2-amino-3-hydroxy-4-methylpentanoic acid

5-Isopropyl-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester

Refernces