tigecycline hydrochloride

Base Information

• Chemical Name: tigecycline hydrochloride
• CAS No.: 197654-04-9
• Molecular Formula: C₂₉H₃₉N₅O₈*ClH
• Molecular Weight: 622.118
• Mol file: 197654-04-9.mol

Synonyms:

Chemical Property of tigecycline hydrochloride

Chemical Property:

Purity/Quality:

>98% ^*data from raw suppliers

Tigecyclinehydrochloride 98+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tigecycline hydrochloride

There total 2 articles about tigecycline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

tigecycline (220620-09-7) → tigecycline hydrochloride (197654-04-9)

Guidance literature:

tigecycline; In acetone; at 20 ℃; for 1.83333h;

With hydrogenchloride; In water; acetone; at 20 ℃; for 5h; Product distribution / selectivity;

Reference yield:

(6aR,7aS,8S,11aS)-2-[(tert-butylamino)methyl]-5,8-bis(dimethylamino)-9,11a,12-trihydroxy-11,13-dioxo-6,6a,7,7a,8,11,11a,13-octahydrotetraceno[2,1-d][1,3]oxazol-10-carboxamide hydrochloride → tigecycline hydrochloride (197654-04-9)

Guidance literature:

With water; for 24h; Acidic aqueous solution;

upstream raw materials:

tigecycline

Refernces

• 1、 -. "TIGECYCLINE AND METHODS OF PREPARATION". Page/Page column 68. . Retrieved 2010/11/25.
• 2、 -. "TIGECYCLINE AND METHODS OF PREPARING 9-AMINOMINOCYCLINE". Page/Page column 67-68. . Retrieved 2010/11/25.