3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide

Base Information

• Chemical Name: 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide
• CAS No.: 718630-59-2
• Molecular Formula: C19H31N5O2
• Molecular Weight: 361.48174
• Mol file: 718630-59-2.mol

Synonyms:N-[6, 6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1, 4-dihydropyrrolo[3, 4-c]pyrazol-3-yl]-3-methyl-butanamide;

Chemical Property of 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide

Chemical Property:

• Boiling Point: 596.226 °C at 760 mmHg
• PKA: 13.74±0.40(Predicted)
• Flash Point: 314.386 °C
• PSA: 84.82000
• Density: 1.176 g/cm³
• LogP: 2.83870
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol(Slightly)

Purity/Quality:

99% ^*data from raw suppliers

PHA-793887 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors.