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5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate

Base Information Edit
  • Chemical Name:5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate
  • CAS No.:239463-85-5
  • Molecular Formula:C22H25N3O2.C4H6O6
  • Molecular Weight:513.547
  • Hs Code.:
  • Mol file:239463-85-5.mol
5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate

Synonyms:3-{5[(2R)-2-aminoprppyl]-7-cyano-2,3-dihydro-1H-indol-1-yl}propyl benzoate monotartaric acid salt; (R)-5-(2-aminopropyl)-1-(3-benzoyloxypropyl) Indoline-7-Carbonitrile Tartaric acid; 5-[(2R)-2-AMINOPROPYL]-1-[3-(BENZOYLOXY)PROPYL]-2,3-DIHYDRO-1H-INDOLE-7-CARBONITRILE (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE; (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate; 3-(5-((R)-2-aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate L-tartrate; 1-(3-benzoyloxypropyl)-7-cyano-5-(2-aminopropyl)-2,3-dihydroindole; 查看更多英文别名 收起

Suppliers and Price of 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile(2R,3R)-2,3-Dihydroxybutanedioate
  • 10g
  • $ 1240.00
  • Matrix Scientific
  • (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl-benzoate (2R,3R)-2,3-dihydroxysuccinate 95+%
  • 5g
  • $ 1183.00
  • Matrix Scientific
  • (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl-benzoate (2R,3R)-2,3-dihydroxysuccinate 95+%
  • 1g
  • $ 420.00
  • Matrix Scientific
  • (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl-benzoate (2R,3R)-2,3-dihydroxysuccinate 95+%
  • 250mg
  • $ 189.00
  • Labseeker
  • 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-Indole-7-carbonitrile tartarate 98
  • 1g
  • $ 250.00
  • Labseeker
  • 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-Indole-7-carbonitrile tartarate 98
  • 5g
  • $ 433.00
  • Crysdot
  • (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propylbenzoate(2R,3R)-2,3-dihydroxysuccinate 95+%
  • 5g
  • $ 297.00
  • Crysdot
  • (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propylbenzoate(2R,3R)-2,3-dihydroxysuccinate 95+%
  • 10g
  • $ 446.00
  • ChemScene
  • (R)-3-(5-(2-aminopropyl)-7-cyanoindolin-1-yl)propylbenzoate(2R,3R)-2,3-dihydroxysuccinate
  • 5g
  • $ 254.00
  • ChemScene
  • (R)-3-(5-(2-aminopropyl)-7-cyanoindolin-1-yl)propylbenzoate(2R,3R)-2,3-dihydroxysuccinate
  • 1g
  • $ 83.00
Total 154 raw suppliers
Chemical Property of 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Edit
Chemical Property:
  • PSA:194.41000 
  • LogP:1.70028 
  • Storage Temp.:Inert atmosphere,Room Temperature 
  • Solubility.:DMSO (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methanol (Sli 
Purity/Quality:

99% *data from raw suppliers

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile(2R,3R)-2,3-Dihydroxybutanedioate *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-Dihydroxybutanedioate is an intermediate of Silodosin (S465000) which is an α1a-adrenoceptor antagonist and used in the treatment of benign prostatic hypertophy.
Technology Process of 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate

There total 62 articles about 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
C38H39N3O4; With palladium on activated charcoal; hydrogen;
L-Tartaric acid; Inert atmosphere;
Guidance literature:
C42H41N3O4; With palladium on activated charcoal; hydrogen;
L-Tartaric acid; Inert atmosphere;
Guidance literature:
3-(5-(2-((tert-butoxycarbonyl)amino)propyl)-7-cyanoindolin-1-yl)propylbenzoate; With hydrogenchloride; In chloroform; water; at 25 - 30 ℃; for 5h;
L-Tartaric acid; In water; acetone; at 20 - 25 ℃; for 12h;
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