3-NITROPHENETHYLAMINE HYDROCHLORIDE

Base Information

• Chemical Name: 3-NITROPHENETHYLAMINE HYDROCHLORIDE
• CAS No.: 19008-62-9
• Molecular Formula: C8H11ClN2O2
• Molecular Weight: 202.641
• Hs Code.: 2921499090
• Mol file: 19008-62-9.mol

Synonyms:Benzeneethanamine, 3-nitro-, monohydrochloride(9CI);Phenethylamine, m-nitro-, monohydrochloride(7CI,8CI);2-(3-Nitrophenyl)ethanamine hydrochloride;3-Nitrophenethylamine hydrochloride;m-Nitrophenethylaminehydrochloride;

Chemical Property of 3-NITROPHENETHYLAMINE HYDROCHLORIDE

Chemical Property:

• Melting Point: 211-215 °C
• PSA: 71.84000
• LogP: 3.12150

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Nitro-phenethylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3-NITROPHENETHYLAMINE HYDROCHLORIDE

There total 2 articles about 3-NITROPHENETHYLAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(3-nitrophenyl)acetic acid amide (5247-25-6) → 1-(3-nitrophenyl)-2-ethanamine hydrochloride (19008-62-9)

Guidance literature:

With borane-THF; In tetrahydrofuran; at 20 - 70 ℃;

Reference yield:

3-(3-nitrophenyl)propanoic acid (1664-57-9) → 1-(3-nitrophenyl)-2-ethanamine hydrochloride (19008-62-9)

Guidance literature:

With hydrogenchloride; sodium azide; Multistep reaction; 2) ether;

DOI:10.1002/recl.19921110103

Reference yield: 100.0%

1-(3-nitrophenyl)-2-ethanamine hydrochloride (19008-62-9) + methanesulfonyl chloride (124-63-0) → N-methylsulfonyl-m-nitrophenylethylamine (273405-00-8)

Guidance literature:

With triethylamine; In dichloromethane; at -20 - 20 ℃; for 17h; Inert atmosphere;

upstream raw materials:

3-(3-nitrophenyl)propanoic acid

2-(3-nitrophenyl)acetic acid amide

Downstream raw materials:

[2-(3-Nitro-phenyl)-ethyl]-urea

1-[2-(3-Nitro-phenyl)-ethyl]-imidazolidine-2,4,5-trione

ethyl 1-(2-(3-nitrophenyl)ethyl)-2,4,5-trioxoimidazolidine-3-acetate

N-(3-nitrophenethyl)-2,2,2-trifluoroacetamide

Refernces

• 1、 Hoefnagel, A. J.,Vos, R. H. de,Wepster, B. M.. "Substituent effects. 14. Anomalous dissociation constants in water-organic solvent mixtures: benzylammonium ions and related systems". . p. 22 - 28. Retrieved 2007/10/02.