(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one

Base Information Edit

Chemical Name:(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one
CAS No.:55094-52-5
Molecular Formula:C₂₆H₂₆O₅
Molecular Weight:418.489
Hs Code.:
European Community (EC) Number:851-368-1
DSSTox Substance ID:DTXSID00451513
Nikkaji Number:J825.800G
Wikidata:Q72509861
Mol file:55094-52-5.mol

Synonyms:55094-52-5;(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one;2,3,5-TRI-O-BENZYL-D-RIBONOLACTONE;2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone;Remdesivir intermediate;(3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-one;C26H26O5;(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)-methyl)dihydrofuran-2(3H)-one;MFCD08703966;Remedesivir intermediate;2,3,5-Tri-O-benzyl-D-ribonic Acid 1,4-lactone;AntinCoV drug intermediate;Anti-nCoV drug intermediate;SCHEMBL3304205;DTXSID00451513;EX-A3436;ZB1791;AKOS016002138;AC-32444;DS-17179;T3955;W10947;2,3,5-Tri-O-benzyl-D-ribonic acid-1,4-lactone;A870283;W-203078;2-O,3-O,5-O-Tribenzyl-D-ribonic acid gamma-lactone;Anticovid-19 intermediate 2,3,5-Tri-O-benzyl-D-ribonolactone;Anti-COVID-19 intermediate 2,3,5-Tri-O-benzyl-D-ribonolactone;(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyldihydrofuran-2(3H)-one;(3R,4R,5R)-3,4-Bis(benzyloxy)-5-[(benzyloxy)methyl]oxolan-2-one (non-preferred name)

Suppliers and Price of (3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
1g
$ 355.00

TRC
2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
25g
$ 175.00

Medical Isotopes, Inc.
2-3-5-Tri-O-benzyl-D-ribono-1-4-lactone
5 g
$ 525.00

Matrix Scientific
(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)-methyl)dihydrofuran-2(3H)-one 95+%
1g
$ 1647.00

Matrix Scientific
(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)-methyl)dihydrofuran-2(3H)-one 95+%
250mg
$ 742.00

Crysdot
(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 98%
5g
$ 44.00

Crysdot
(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 98%
10g
$ 70.00

Crysdot
(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 98%
25g
$ 140.00

Crysdot
(3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 98%
100g
$ 480.00

Chemenu
2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone 95+%
1000g
$ 640.00

Total 96 raw suppliers

Chemical Property of (3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one Edit

Chemical Property:

Melting Point:54-55 °C
Boiling Point:576.8±50.0 °C(Predicted)
PSA：53.99000
Density:1.21±0.1 g/cm3(Predicted)
LogP:4.29940
Storage Temp.:2-8°C
Solubility.:Chloroform (Sparingly), DMSO (Slightly, Sonicated), Methanol (Slightly)
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:418.17802393
Heavy Atom Count:31
Complexity:520

Purity/Quality:

99%min, ^*data from raw suppliers

2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COCC2C(C(C(=O)O2)OCC3=CC=CC=C3)OCC4=CC=CC=C4
Isomeric SMILES:C1=CC=C(C=C1)COC[C@@H]2[C@H]([C@H](C(=O)O2)OCC3=CC=CC=C3)OCC4=CC=CC=C4

Technology Process of (3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one

There total 22 articles about (3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.2%

: 16838-89-4
2,3,5-tri-O-benzyl-D-ribofuranose

: 14233-64-8,134307-32-7,55094-52-5
(3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-dihydro-furan-2-one

Guidance literature:: With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium thiosulfate; potassium bromide; In dichloromethane; water; at 10 - 15 ℃; for 0.00416667h; under 1125.11 - 2250.23 Torr; Temperature;