Magnesium;1-bromo-2-methanidylbenzene;bromide

Base Information

• Chemical Name: Magnesium;1-bromo-2-methanidylbenzene;bromide
• CAS No.: 56812-60-3
• Molecular Formula: C7H6Br2Mg
• Molecular Weight: 274.238
• Hs Code.: 29310099
• DSSTox Substance ID: DTXSID00446186
• Mol file: 56812-60-3.mol

Synonyms:magnesium;1-bromo-2-methanidylbenzene;bromide;DTXSID00446186

Chemical Property of Magnesium;1-bromo-2-methanidylbenzene;bromide

Chemical Property:

• Vapor Pressure: 1.2mmHg at 25°C
• Refractive Index: ">
• Boiling Point: 34.6 °C at 760 mmHg
• Flash Point: 1 °F
• PSA: 0.00000
• Density: 0.770 g/cm³
• LogP: 3.61040
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 273.86662
• Heavy Atom Count: 10
• Complexity: 70.8

Purity/Quality:

98%Min ^*data from raw suppliers

2-Bromobenzylmagnesium bromide solution 0.25M in diethyl ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F+, C
• Hazard Codes: F+,C,Xn
• Statements: 12-14-19-22-34-66-67
• Safety Statements: 16-26-33-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [CH2-]C1=CC=CC=C1Br.[Mg+2].[Br-]

Technology Process of Magnesium;1-bromo-2-methanidylbenzene;bromide

There total 3 articles about Magnesium;1-bromo-2-methanidylbenzene;bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

+ 1-Bromo-2-bromomethyl-benzene (3433-80-5) → (2-bromobenzyl)magnesium bromide (56812-60-3) + 9-(2-Bromo-benzyl)-anthracene

Guidance literature:

using 2 eq. of Mg-complex;

DOI:10.1039/c39880000289

Reference yield: 12.0%

1-Bromo-2-bromomethyl-benzene (3433-80-5) → 1,2-bis(2-bromophenyl)ethane (59485-34-6) + (2-bromobenzyl)magnesium bromide (56812-60-3)

Guidance literature:

With ; In tetrahydrofuran; diethyl ether; at 20 ℃; for 0.5h; Yields of byproduct given; using 1eq.;

DOI:10.1039/c39880000289

Reference yield:

1-Bromo-2-bromomethyl-benzene (3433-80-5) → (2-bromobenzyl)magnesium bromide (56812-60-3) + BrMgC6H4CH2CH2C6H4MgBr (113419-93-5)

Guidance literature:

With magnesium; In diethyl ether; Product distribution; various dihalides in various solvents;

DOI:10.1016/0022-328X(87)80301-7

upstream raw materials:

1-Bromo-2-bromomethyl-benzene

Downstream raw materials:

1-(2'-bromophenyl)-2,3-pentadiene

3-benzylcyclohex-2-en-1-one

(2?bromobenzyl)(4?methylphenyl) sulfide

Refernces

• 1、 Boer, H. J. R. De,Akkerman, O. S.,Bickelhaupt, F.. "An Investigation of the Di-Grignard Approach to Metallabenzocyclobutenes of Group 14". . p. 291 - 306. Retrieved 2007/10/02.