(3R,5S)-rel-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate

Base Information Edit

Chemical Name:(3R,5S)-rel-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate
CAS No.:129779-30-2
Molecular Formula:C11H22N2O2
Molecular Weight:214.308
Hs Code.:2933599090
European Community (EC) Number:825-251-0
DSSTox Substance ID:DTXSID70445383
Wikidata:Q76416023
Mol file:129779-30-2.mol

Synonyms:129779-30-2;(3R,5S)-rel-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate;1152111-14-2;cis-1-boc-3,5-dimethylpiperazine;1-BOC-CIS-3,5-DIMETHYL-PIPERAZINE;Tert-butyl (3R,5S)-3,5-dimethylpiperazine-1-carboxylate;(3S,5R)-TERT-BUTYL 3,5-DIMETHYLPIPERAZINE-1-CARBOXYLATE;tert-butyl (3S,5R)-3,5-dimethylpiperazine-1-carboxylate;cis-1-Boc-3,5-dimethylpiperazin;(3R,5S)-tert-butyl 3,5-Dimethylpiperazine-1-carboxylate;(3S,5R)-rel-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate;1-Piperazinecarboxylic acid, 3,5-dimethyl-, 1,1-dimethylethyl ester, cis-;cis-3,5-Dimethyl-piperazine-1-carboxylic acid tert-butyl ester;MFCD06795911;SCHEMBL64563;DTXSID70445383;NUZXPHIQZUYMOR-DTORHVGOSA-N;cis-1-Boc-3,5-dimethyl-piperazine;AKOS016015106;DS-7286;AC-30162;AM803143;EN300-154309;1-Boc-cis-3,5-dimethyl-piperazine, AldrichCPR;cis-1-tert-butoxycarbonyl-3,5-dimethyl piperazine;(cis) 2,6-Dimethyl-4-tertbutyloxycarbonylpiperizine;N-(tert-butoxycarbonyl)-cis-3,5-dimethylpiperazine;tert-butyl cis-3,5-dimethyl-1-piperazinecarboxylate;tert-butyl cis-3,5-dimethylpiperazine-1-carboxylate;tert-butyl (cis)-3,5-dimethyl-1-piperazinecarboxylate;tert-butyl(cis)-3,5-dimethyl-1-piperazinecarboxylate;tertbutyl (cis)-3,5-dimethyl-1-piperazinecarboxylate;(3 S,5R)-tert-butyl 3,5-dimethylpiperazine-1-carboxylate;(3S*,5R*)-tert-butyl 3,5-dimethylpiperazine-1-carboxylate;1-(1,1-Dimethylethoxycarbonyl)-cis-3,5-dimethylpiperazine;CIS-TERT-BUTYL 3,5-DIMETHYLPIPERAZINE-1-CARBOXYLATE;(3R,5S)-rel-tert-Butyl3,5-dimethylpiperazine-1-carboxylate;cis-3,5-dimethylpiperazine-1-carboxylic acid tert-butyl ester;(3S,5R)-3,5-dimethyl-piperazine-1-carboxylic acid tert-butyl ester;(cis)-3,5-dimethyl-piperazine-1-carboxylic acid tert-butyl ester;1,1-dimethylethyl (3R,5S)-3,5-dimethyl-1-piperazinecarboxylate;(3R,5S)-3,5-dimethyl-1-piperazinecarboxylic acid, 1,1-dimethylethyl ester;(3R,5S)-3,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-PIPERAZINECARBOXYLIC ACID, 3,5-DIMETHYL-, 1,1-DIMETHYLETHYL ESTER, (3R,5S)-REL-

Suppliers and Price of (3R,5S)-rel-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
SOCS3
48Tests
$ 588.00

Usbiological
SOCS3
48Tests
$ 588.00

Usbiological
SOCS3
96Tests
$ 729.00

Usbiological
SOCS3
100ug
$ 490.00

TRC
1-Boc-cis-3,5-dimethyl-piperazine
2.5g
$ 205.00

Matrix Scientific
1-Boc-3,5-Dimethylpiperazine 95+%
1g
$ 119.00

Matrix Scientific
1-Boc-3,5-Dimethylpiperazine 95+%
5g
$ 357.00

Matrix Scientific
1-Boc-3,5-Dimethylpiperazine 95+%
10g
$ 604.00

J&W Pharmlab
cis-1-Boc-3,5-dimethyl-piperazine 96%
100g
$ 1590.00

Crysdot
(3R,5S)-rel-tert-Butyl3,5-dimethylpiperazine-1-carboxylate 98%
25g
$ 210.00

Total 36 raw suppliers

Chemical Property of (3R,5S)-rel-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate Edit

Chemical Property:

Vapor Pressure:0.004mmHg at 25°C
Refractive Index:1.452
Boiling Point:279.738 °C at 760 mmHg
PKA:8.58±0.60(Predicted)
Flash Point:122.982 °C
PSA：41.57000
Density:0.971g/cm³
LogP:1.87040
Storage Temp.:-20°C
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:214.168127949
Heavy Atom Count:15
Complexity:225

Purity/Quality:

98%,99%, ^*data from raw suppliers

SOCS3 ^*data from reagent suppliers

Safty Information:

Pictogram(s): N
Hazard Codes:N
Statements: 36/37/38-50
Safety Statements: 26-61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CN(CC(N1)C)C(=O)OC(C)(C)C
Isomeric SMILES:C[C@@H]1CN(C[C@@H](N1)C)C(=O)OC(C)(C)C
Uses 1-Boc-cis-3,5-dimethyl-piperazine is used in the identification of 7-(3-(Piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent, selective and orally bioavailable PI3Kδ inhibitors.
Description 1-BOC-3,5- dimethylpiperazine is a heterocyclic derivative and can be used as pharmaceutical intermediates.

Technology Process of (3R,5S)-rel-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate

There total 5 articles about (3R,5S)-rel-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%