2,6-BIS(2-PYRIDYL)-4(1H)-PYRIDONE

Base Information

• Chemical Name: 2,6-BIS(2-PYRIDYL)-4(1H)-PYRIDONE
• CAS No.: 128143-88-4
• Molecular Formula: C15H11N3O
• Molecular Weight: 249.27
• Hs Code.: 29333990
• Mol file: 128143-88-4.mol

Synonyms:2,6-Bis(pyridin-2-yl)-4-pyridone;2,6-Bis(2-pyridyl)-1,4-dihydropyridin-4-one;2,6-Bis(2-pyridyl)-4(1H)-pyridone;2,6-Bis(2'-pyridyl)-4-pyridone;[2,2':6',2''-terpyridin]-4'-ol;

Chemical Property of 2,6-BIS(2-PYRIDYL)-4(1H)-PYRIDONE

Chemical Property:

• Melting Point: 168-170 °C(lit.)
• Boiling Point: 505.5 °C at 760 mmHg
• PKA: -0.16±0.69(Predicted)
• Flash Point: 259.5 °C
• PSA: 58.64000
• Density: 1.269 g/cm³
• LogP: 2.49890
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2,6-Bis(2-pyridyl)-4(1H)-pyridone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Description: 2,6-Bis(2-pyridyl)-4(1H)-pyridone?belongs to heterocyclic derivatives and can be used as pharmaceutical intermediates.
• Uses: 2,6-Bis(2-pyridyl)-4(1H)-pyridone can be used a heterocyclic building block to prepare 4′-substituted terpyridines by reacting with ω-substituted primary alcohols or nucleosides via Mitsunobu reaction. It is also used to prepare cyclotriphosphazene ligands with pendant terpyridine moieties.

Technology Process of 2,6-BIS(2-PYRIDYL)-4(1H)-PYRIDONE

There total 5 articles about 2,6-BIS(2-PYRIDYL)-4(1H)-PYRIDONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,2':6',2'-terpyridin-4'-(1'H)-one acetic acid adduct (474745-38-5) → 2,2':6',2''-Terpyridin-4'(1'H)-one (128143-88-4)

Guidance literature:

With sodium hydrogencarbonate; In chloroform; water;

DOI:10.1071/CH13571

Reference yield: 94.0%

1,5-bis(2′-pyridyl)pentane-1,3,5-trione (128143-87-3) → 2,2':6',2''-Terpyridin-4'(1'H)-one (128143-88-4)

Guidance literature:

With ammonium acetate; In ethanol; for 6h; Heating;

DOI:10.1039/DT9950001769

Reference yield: 32.0%

4'-(methylsulfonyl)-2,2':6',2''-terpyridine (81874-51-3) → 2,2':6',2''-Terpyridin-4'(1'H)-one (128143-88-4)

Guidance literature:

With potassium hydroxide; dibenzo-18-crown-6; In 1,2-dimethoxyethane; for 48h; Heating;

DOI:10.1021/jo00015a050

upstream raw materials:

1,5-bis(2′-pyridyl)pentane-1,3,5-trione

4'-(methylsulfonyl)-2,2':6',2''-terpyridine

ethyl-2-picolinate

2,2':6',2'-terpyridin-4'-(1'H)-one acetic acid adduct

Downstream raw materials:

4'-Chloro-2,2':6',2''-terpyridine

4'-bromo-2,2':6',2''-terpyridine

O-(1-(4-((2,2':6',2''-terpyridin-4'-yloxy)methyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-(4-(((tetrahydro-2H-pyran-2-yl)-oxy)methyl)phenyl)propyl)hydroxylamine

1-((4-methoxyphenyl)diphenylmethoxy)-4-(2,2':6',2''-terpyridin-4'-yloxy)butane

Refernces

• 1、 Nair, Neelima V.,Zhou, Rongwei,Thummel, Randolph P.. "The synthesis, photophysical properties and water oxidation studies of a series of novel photosensitizer–catalyst assemblies". . p. 27 - 39. Retrieved 2017.
• 2、 Aguiló, Elisabet,Moro, Artur J.,Gavara, Raquel,Alfonso, Ignacio,Pérez, Yolanda,Zaccaria, Francesco,Guerra, Célia Fonseca,Malfois, Marc,Baucells, Clara,Ferrer, Montserrat,Lima, Jo?o Carlos,Rodríguez, Laura. "Reversible Self-Assembly of Water-Soluble Gold(I) Complexes". . p. 1017 - 1028. Retrieved 2018.
• 3、 Majouga,Romashkina,Kashaev,Rahimov,Beloglazkina,Zyk. "New organic ligands of the terpyridine series: Modification of gold nanoparticles, preparation of coordination compounds with Cu(I), catalysis of oxidation reactions". . p. 1076 - 1083. Retrieved 2010.
• 4、 Huang, Wenyi,Han, Chang Dae. "Ruthenium(II) complex-induced dispersion of montmorillonite in a segmented main-chain liquid-crystalline polymer having side-chain terpyridine group". . p. 8207 - 8209. Retrieved 2006.