IFLAB-BB F1962-0261

Base Information

• Chemical Name: IFLAB-BB F1962-0261
• CAS No.: 63497-60-9
• Molecular Formula: C8H4ClNO3
• Molecular Weight: 197.578
• Hs Code.: 2934999090
• Mol file: 63497-60-9.mol

Synonyms:Isatoic anhydride, 3-chloro- (6CI);IFLAB-BB F1962-0261;3-Chloro-2H-3,1-benzoxazine-2,4(1H)-dione;3-Chloroisatoic anhydride;

Chemical Property of IFLAB-BB F1962-0261

Chemical Property:

• Melting Point: 227-232 °C
• Refractive Index: 1.6
• PKA: 9.70±0.20(Predicted)
• PSA: 63.07000
• Density: 1.54 g/cm³
• LogP: 1.13470

Purity/Quality:

98% ^*data from raw suppliers

8-Chloro-1H-benzo[d][1,3]oxazine-2,4-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of IFLAB-BB F1962-0261

There total 6 articles about IFLAB-BB F1962-0261 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

bis(trichloromethyl) carbonate (32315-10-9) + 2-amino-3-chlorobenzoic acid (6388-47-2) → 8-chloro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione (63497-60-9)

Guidance literature:

With pyridine; In dichloromethane; acetonitrile; at 20 ℃; for 5h;

Reference yield: 85.0%

7-chloroisatin (7477-63-6) → 8-chloro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione (63497-60-9)

Guidance literature:

With sulfuric acid; dihydrogen peroxide; In water; acetic acid; at 60 - 70 ℃; for 2h;

Reference yield: 55.0%

→ 8-chloro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione (63497-60-9)

Guidance literature:

upstream raw materials:

7-chloroisatin

phosgene

2-amino-3-chlorobenzoic acid

4-chloro-1H-isoindole-1,3(2H)-dione

Downstream raw materials:

2-amino-N-(4-bromophenyl)-3-chlorobenzamide

2-amino-3-chloro-N-thiazol-2-yl-benzamide

2-amino-3-chloro-benzamide

Refernces

• 1、 -. "Dihydroquinoline compound and preparation method and application thereof". Paragraph 0052-0056. . Retrieved 2020/06/09.
• 2、 Wang, Baolei,Wang, Hongxue,Liu, Hang,Xiong, Lixia,Yang, Na,Zhang, Yan,Li, Zhengming. "Synthesis and structure-insecticidal activity relationship of novel phenylpyrazole carboxylic acid derivatives containing fluorine moiety". . p. 739 - 745. Retrieved 2019/08/20.