Isoniazid-D4

Base Information

• Chemical Name: Isoniazid-D4
• CAS No.: 774596-24-6
• Molecular Formula: C6H3 D4 N3 O
• Molecular Weight: 137.14
• Mol file: 774596-24-6.mol

Synonyms:Isoniazid-D4;4-Pyridine-2,3,5,6-d4-carboxylic Acid Hydrazide;FSR-3-d;Isonicotinylhydrazine-d4;RP-5015-d4;Tubazid-d4;(4-Pyridine-2,3,5,6-D-carboxylic Acid Hydrazide;FSR-3-d3

Chemical Property of Isoniazid-D4

Chemical Property:

• Melting Point: 171.40C
• Refractive Index: 1.584
• PSA: 68.01000
• Density: 1.281g/cm³
• LogP: 0.77630
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

95-99% ^*data from raw suppliers

Isoniazid-d4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).