1-(tri-n-butylstannyl)-3,5-bis(trifluoromethyl)benzene

Base Information

• Chemical Name: 1-(tri-n-butylstannyl)-3,5-bis(trifluoromethyl)benzene
• CAS No.: 717918-62-2
• Molecular Formula: C₂₀H₃₀F₆Sn
• Molecular Weight: 503.159
• Mol file: 717918-62-2.mol

Synonyms:1-(tri-n-butylstannyl)-3,5-bis(trifluoromethyl)benzene

Chemical Property of 1-(tri-n-butylstannyl)-3,5-bis(trifluoromethyl)benzene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(tri-n-butylstannyl)-3,5-bis(trifluoromethyl)benzene

There total 1 articles about 1-(tri-n-butylstannyl)-3,5-bis(trifluoromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3,6-bis(trifluoromethyl)bromobenzene (328-70-1) + tributyltin chloride (1461-22-9) → 1-(tri-n-butylstannyl)-3,5-bis(trifluoromethyl)benzene (717918-62-2)

Guidance literature:

With n-butyllithium; In diethyl ether; hexane; (N2); addn. of fluorine compd. to ether, addn. of a soln. of lithium compd. in hexanes at -78°C, stirring for 10 min, addn. of tin compd., stirring at -78°C for 2 h, stirring for 16 h at room temp.; evapn., addn. of CH2Cl2 and water, washing aq. phase with CH2Cl2, dryingcombined org. phases (MgSO4), filtration, evapn., vac. distn.; elem. an al.;

DOI:10.1021/om0400189

Reference yield: 80.0%

2,8-dibromo-indeno[1,2-b]fluorene-6,12-dione (853234-57-8) + 1-(tri-n-butylstannyl)-3,5-bis(trifluoromethyl)benzene (717918-62-2) → C36H14F12O2 (1104877-02-2)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; Inert atmosphere; Reflux;

DOI:10.1002/anie.201104797

Reference yield: 67.0%

1-(tri-n-butylstannyl)-3,5-bis(trifluoromethyl)benzene (717918-62-2) + 2,5-dibromo-3,4-dinitrothiophene (52431-30-8) → 2,5-bis(3,5-bis-trifluoromethylphenyl)-3,4-dinitro-thiophene

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; triphenyl-arsane; In toluene; at 80 ℃; for 12h;

DOI:10.1002/chem.200601298

upstream raw materials:

3,6-bis(trifluoromethyl)bromobenzene

tributyltin chloride

Downstream raw materials:

1-(trichlorogermyl)-3,5-bis(trifluoromethyl)benzene

tributyltin chloride

C₃₆H₁₄F₁₂O₂

C₅₈H₅₈F₁₂O₂Si₂

Refernces

• 1、 Akram, Manjur O.,Shinde, Popat S.,Chintawar, Chetan C.,Patil, Nitin T.. "Gold(i)-catalyzed cross-coupling reactions of aryldiazonium salts with organostannanes". supporting information. p. 2865 - 2869. Retrieved 2018/05/03.