trans-4-(acetamidomethyl)cyclohexylcarbonylhydrazine

Base Information

• Chemical Name: trans-4-(acetamidomethyl)cyclohexylcarbonylhydrazine
• CAS No.: 79697-32-8
• Molecular Formula: C₁₀H₁₉N₃O₂
• Molecular Weight: 213.28
• Mol file: 79697-32-8.mol

Synonyms:trans-4-(acetamidomethyl)cyclohexylcarbonylhydrazine

Chemical Property of trans-4-(acetamidomethyl)cyclohexylcarbonylhydrazine

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of trans-4-(acetamidomethyl)cyclohexylcarbonylhydrazine

There total 3 articles about trans-4-(acetamidomethyl)cyclohexylcarbonylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

methyl 4-(acetamidomethyl)cyclohexane-1-carboxylate (51782-10-6) → trans-4-(acetamidomethyl)cyclohexylcarbonylhydrazine (79697-32-8)

Guidance literature:

With hydrazine hydrate; In ethanol; for 4h; Heating;

DOI:10.1248/cpb.29.1935

Reference yield:

4-aminomethyl-cyclohexanecarboxylic acid (1197-17-7,1197-18-8,701-54-2) → trans-4-(acetamidomethyl)cyclohexylcarbonylhydrazine (79697-32-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / HCl / 5 h / Heating

2: 80 percent / NaHCO₃ / H₂O

3: 69 percent / hydrazine hydrate / ethanol / 4 h / Heating

With hydrogenchloride; sodium hydrogencarbonate; hydrazine hydrate; In ethanol; water;

DOI:10.1248/cpb.29.1935

Reference yield:

4-aminomethyl-cyclohexanecarboxylic acid methyl ester (23199-14-6) → trans-4-(acetamidomethyl)cyclohexylcarbonylhydrazine (79697-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / NaHCO₃ / H₂O

2: 69 percent / hydrazine hydrate / ethanol / 4 h / Heating

With sodium hydrogencarbonate; hydrazine hydrate; In ethanol; water;

DOI:10.1248/cpb.29.1935

upstream raw materials:

methyl 4-(acetamidomethyl)cyclohexane-1-carboxylate

4-aminomethyl-cyclohexanecarboxylic acid

4-aminomethyl-cyclohexanecarboxylic acid methyl ester

Refernces