methyl N-(diphenylmethylene)-5,6-dimethoxytryptophanate

Base Information

• Chemical Name: methyl N-(diphenylmethylene)-5,6-dimethoxytryptophanate
• CAS No.: 142683-35-0
• Molecular Formula: C₂₇H₂₆N₂O₄
• Molecular Weight: 442.514
• Mol file: 142683-35-0.mol

Synonyms:methyl N-(diphenylmethylene)-5,6-dimethoxytryptophanate

Chemical Property of methyl N-(diphenylmethylene)-5,6-dimethoxytryptophanate

Chemical Property:

Purity/Quality:

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Technology Process of methyl N-(diphenylmethylene)-5,6-dimethoxytryptophanate

There total 1 articles about methyl N-(diphenylmethylene)-5,6-dimethoxytryptophanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

Methyl N-(diphenylmethylene)-α,β-didehydroalaninate (118553-21-2) + 5,6-dimethoxyindole (14430-23-0) → methyl N-(diphenylmethylene)-5,6-dimethoxytryptophanate (142683-35-0)

Guidance literature:

With ethylaluminum dichloride; In hexane; dichloromethane; at 0 ℃; for 1h;

DOI:10.1002/jhet.5570290205

Reference yield: 65.0%

methyl N-(diphenylmethylene)-5,6-dimethoxytryptophanate (142683-35-0) → 1,1-diphenyl-3-carbomethoxy-6,7-dimethoxy-1,2,3,4-tetrahydro-β-carboline (142683-49-6)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 10h; Heating;

DOI:10.1002/jhet.5570290205

upstream raw materials:

Methyl N-(diphenylmethylene)-α,β-didehydroalaninate

5,6-dimethoxyindole

Downstream raw materials:

1,1-diphenyl-3-carbomethoxy-6,7-dimethoxy-1,2,3,4-tetrahydro-β-carboline

Refernces