4'-(4-Iodophenylsulfamoyl)acetanilide

Base Information

• Chemical Name: 4'-(4-Iodophenylsulfamoyl)acetanilide
• CAS No.: 19837-94-6
• Molecular Formula: C₁₄H₁₃IN₂O₃S
• Molecular Weight: 416.239
• Mol file: 19837-94-6.mol

Synonyms:N-{4-[(4-iodophenyl)sulfamoyl]phenyl}acetamide

Chemical Property of 4'-(4-Iodophenylsulfamoyl)acetanilide

Chemical Property:

• PKA: 8.46±0.10(Predicted)
• Density: 1.780±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

N-(4-{[(4-iodophenyl)amino]sulfonyl}phenyl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-(4-Iodophenylsulfamoyl)acetanilide

There total 1 articles about 4'-(4-Iodophenylsulfamoyl)acetanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

p-acetylaminobenzenesulfonyl chloride (121-60-8) + p-aminoiodobenzene (540-37-4) → N-{4-[(4-iodophenyl)sulfamoyl]phenyl}acetamide (19837-94-6)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1016/j.bmcl.2017.08.012

Reference yield: 64.0%

N-{4-[(4-iodophenyl)sulfamoyl]phenyl}acetamide (19837-94-6) → 4-amino-N-(4-iodophenyl)benzene-1-sulfonamide (6965-75-9)

Guidance literature:

With hydrogenchloride; In acetone; at 20 ℃; for 0.0833333h; Cooling with ice;

DOI:10.1016/j.bmcl.2017.08.012

Reference yield: 54.0%

N-{4-[(4-iodophenyl)sulfamoyl]phenyl}acetamide (19837-94-6) → sulfanitran (122-16-7)

Guidance literature:

With 1,10-Phenanthroline; iron(II) sulfate; potassium nitrate; In dimethyl sulfoxide; at 20 ℃; for 48h; UV-irradiation; Inert atmosphere;

DOI:10.1021/acscatal.1c02272

upstream raw materials:

p-acetylaminobenzenesulfonyl chloride

p-aminoiodobenzene

Downstream raw materials:

4-amino-N-(4-iodophenyl)benzene-1-sulfonamide

sulfanitran

Refernces