L-Methionine-methyl-13C

Base Information

• Chemical Name: L-Methionine-methyl-13C
• CAS No.: 49705-26-2
• Molecular Formula: C5H11 N O2 S
• Molecular Weight: 150.203
• UNII: 55YCX1IL8T
• Nikkaji Number: J1.279.082A
• Mol file: 49705-26-2.mol

Synonyms:L-Methionine-methyl-13C;49705-26-2;L-Methionine-13C;(Methyl-13C)methionine;(Me-13C)-L-methionine;55YCX1IL8T;(Methyl-13C)-L-methionine;L-Methionine-(methyl-13C);L-(S-Methyl-13C)methionine;UNII-55YCX1IL8T;(2S)-2-amino-4-(113C)methylsulfanylbutanoic acid;Methionine-methyl-13C-methyl-d3;73488-65-0;FFEARJCKVFRZRR-YWQIHCTDSA-N;HY-N0326S3;MFCD00002623;CS-0376154;L-Methionine-(methyl-13C), 99 atom % 13C

Chemical Property of L-Methionine-methyl-13C

Chemical Property:

• Melting Point: 284 °C(lit.)
• PSA: 88.62000
• LogP: 0.85170
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: Aqueous Acid (Slightly), Methanol (Slightly), Water (Sparingly, Heated)
• XLogP3: -1.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 150.05440460
• Heavy Atom Count: 9
• Complexity: 97

Purity/Quality:

98%,99%, ^*data from raw suppliers

L-Methionine-13C ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CSCCC(C(=O)O)N
• Isomeric SMILES: [13CH3]SCC[C@@H](C(=O)O)N

Technology Process of L-Methionine-methyl-13C

There total 3 articles about L-Methionine-methyl-13C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

[13C]methyl iodide (4227-95-6) + L-homocysteine (6027-13-0) → [methyl-13C]-L-methionine (49705-26-2)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; for 23h;

DOI:10.1016/S0040-4020(01)85267-4

Reference yield:

→ [methyl-13C]-methionine (49705-26-2)

Guidance literature:

13CH3I, Methionin;

DOI:10.1021/ja00483a048

Reference yield:

→ [methyl-13C]-L-methionine (49705-26-2)

Guidance literature:

upstream raw materials:

[13C]methyl iodide

L-homocysteine

Downstream raw materials:

S-adenosyl-L-methionine

Refernces

• 1、 Hilhorst, Ellen,Chen, Tjoe B. R. A.,Iskander, Atef S.,Pandit, Upendra K.. "Dealkylation of Quaternary Ammonium Salts by Thiolate Anions: A Model of the Cobalamin-independent Methionine Synthase Reaction.". . p. 7837 - 7848. Retrieved 2007/10/02.