(2S,4R)-2-amino-4-hydroxypentanedioic acid

Base Information Edit

Chemical Name:(2S,4R)-2-amino-4-hydroxypentanedioic acid
CAS No.:2485-33-8
Molecular Formula:C₅H₉NO₅
Molecular Weight:163.13
Hs Code.:2922509090
DSSTox Substance ID:DTXSID90331532
Nikkaji Number:J83.286C
Wikidata:Q82096649
Metabolomics Workbench ID:53837
ChEMBL ID:CHEMBL371946
Mol file:2485-33-8.mol

Synonyms:(2S,4R)-2-amino-4-hydroxypentanedioic acid;2485-33-8;erythro-4-hydroxy-L-glutamic acid;L-erythro-4-hydroxyglutamic acid;(2S,4R)-gamma-Hydroxyglutamic acid;L-erythro-4-Hydroxyglutamate;CHEBI:21285;(4S)-4-hydroxy-L-glutamic acid;erythro-4-hydroxy-L-glutamate;(2S,4R)-4-Hydroxy-L-glutamic Acid;erythro-4-hydroxyglutamate;L-erythro-4-hydroxy-glutamate;CHEMBL371946;SCHEMBL5819946;DTXSID90331532;H-(2S,4R)--Hydroxy-Glu-OH;(2S,4R)-4-Hydroxyglutamic Acid;H-(2S,4R)-g-Hydroxy-Glu-OH;L-Glutamic acid,4-hydroxy-,(4R)-;MFCD00672375;(2S,4R)-gamma-Hydroxy-glutamic acid;AKOS006271402;CS-W013253;HY-W012537;MS-22896;C05947;J-015700;(4R)-4-Hydroxy-L-glutamic acid, >=98.0% (TLC);1-Benzyl-4-trifluoromethyl-pyrrolidine-3-carboxylicacid

Suppliers and Price of (2S,4R)-2-amino-4-hydroxypentanedioic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S,4R)-4-Hydroxy-L-glutamicAcid
10mg
$ 165.00

Sigma-Aldrich
(4R)-4-Hydroxy-L-glutamic acid ≥98.0% (TLC)
50mg
$ 497.00

Sigma-Aldrich
(4R)-4-Hydroxy-L-glutamic acid ≥98.0% (TLC)
10mg
$ 196.00

Medical Isotopes, Inc.
(2S,4R)-4-Hydroxy-L-glutamicAcid
100 mg
$ 2200.00

Crysdot
(2S,4R)-2-Amino-4-hydroxypentanedioicacid 95+%
1g
$ 1376.00

Chem-Impex
(2S,4R)-γ-Hydroxy-L-glutamicacid,≥98%(TLC) ≥98%(TLC)
1G
$ 1615.58

Chem-Impex
(2,4)-γ-Hydroxy-L-glutamic acid ≥ 98% (TLC)
25MG
$ 166.00

Chem-Impex
(2S,4R)-γ-Hydroxy-L-glutamicacid,≥98%(TLC) ≥98%(TLC)
250MG
$ 783.91

American Custom Chemicals Corporation
(2S,4R)-2-AMINO-4-HYDROXYPENTANEDIOIC ACID 95.00%
10MG
$ 750.75

AK Scientific
H-(2S,4R)-Gamma-Hydroxy-Glu-OH
250mg
$ 958.00

Total 7 raw suppliers

Chemical Property of (2S,4R)-2-amino-4-hydroxypentanedioic acid Edit

Chemical Property:

Boiling Point:458.7 °C at 760 mmHg
PKA:2.15±0.10(Predicted)
Flash Point:231.2 °C
PSA：120.85000
Density:1.595 g/cm³
LogP:-1.06580
Storage Temp.:-15°C
Solubility.:DMSO (Slightly), Water (Slightly)
XLogP3:-4.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:163.04807239
Heavy Atom Count:11
Complexity:168

Purity/Quality:

99% ^*data from raw suppliers

(2S,4R)-4-Hydroxy-L-glutamicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(C(C(=O)O)N)C(C(=O)O)O
Isomeric SMILES:C([C@@H](C(=O)O)N)[C@H](C(=O)O)O
Uses (2S,4R)-4-Hydroxy-L-glutamic Acid is a metabolite of Glutamic acid (G596960).

Technology Process of (2S,4R)-2-amino-4-hydroxypentanedioic acid

There total 10 articles about (2S,4R)-2-amino-4-hydroxypentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 127-17-3
2-oxo-propionic acid

: 298-12-4
Glyoxilic acid

: 2485-33-8
(2S,4R)-4-hydroxyglutamic acid

Guidance literature:: With L-asparagine; Escherichia coli aspartate transaminase; Pseudomonas aeruginosa A₀A₀₈₁HJP₉ aldolase; water; magnesium chloride; In aq. phosphate buffer; at 20 ℃; for 24h; stereoselective reaction; Kinetics; Enzymatic reaction;
DOI:10.1039/c7cc00742f