(4-Methylpyridin-3-YL)methanamine

Base Information

• Chemical Name: (4-Methylpyridin-3-YL)methanamine
• CAS No.: 1443-42-1
• Molecular Formula: C7H10 N2
• Molecular Weight: 122.17
• Hs Code.: 2933399090
• European Community (EC) Number: 808-900-2
• DSSTox Substance ID: DTXSID50480898
• Wikidata: Q82316027
• Mol file: 1443-42-1.mol

Synonyms:(4-METHYLPYRIDIN-3-YL)METHANAMINE;1443-42-1;(4-Methylpyridin-3-yl)methylamine;3-AMINOMETHYL-4-METHYLPYRIDINE;3-Pyridinemethanamine, 4-methyl-;MFCD06213859;(4-Methyl-3-pyridinyl)methanamine;(4-methyl-3-pyridyl)methanamine;SCHEMBL317755;DTXSID50480898;AB9814;1-(4-Methylpyridin-3-yl)methanamine;AKOS006292548;AM86595;PB14440;TS-01432;BB 0261753;CS-0053195;FT-0681627;(4-methylpyridin-3-yl)methylamine, AldrichCPR;EN300-160160

Chemical Property of (4-Methylpyridin-3-YL)methanamine

Chemical Property:

• Vapor Pressure: 0.0332mmHg at 25°C
• Refractive Index: 1.545
• Boiling Point: 242.8°C at 760 mmHg
• PKA: 8.39±0.29(Predicted)
• Flash Point: 121.3°C
• PSA: 38.91000
• Density: 1.027g/cm³
• LogP: 1.54900
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 122.084398327
• Heavy Atom Count: 9
• Complexity: 83

Purity/Quality:

98%,99%, ^*data from raw suppliers

(4-Methylpyridin-3-yl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-38-41
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=NC=C1)CN

Technology Process of (4-Methylpyridin-3-YL)methanamine

There total 4 articles about (4-Methylpyridin-3-YL)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ ((4-methylpyridin-3-yl)methyl)amine (1443-42-1)

Guidance literature:

With ammonia; hydrogen; In methanol; at 20 ℃; for 2h;

Reference yield: 95.0%

4-methyl-3-pyridinecarboxamide (7250-52-4) → ((4-methylpyridin-3-yl)methyl)amine (1443-42-1)

Guidance literature:

With dimethylsulfide borane complex; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield: 71.0%

3-cyano-4-methylpyridine (5444-01-9) → ((4-methylpyridin-3-yl)methyl)amine (1443-42-1)

Guidance literature:

With sodium tetrahydroborate; iodine; In tetrahydrofuran; at 20 ℃; for 17.5h;

upstream raw materials:

4-methyl-3-pyridinecarboxamide

4-methylnicotinic acid

3-cyano-4-methylpyridine

Downstream raw materials:

C₂₀H₁₉N₃O₃S

C₁₄H₁₄ClN₃O₃S

Refernces

• 1、 -. "Pyridine methylamine compound and preparation method thereof". Paragraph 0102-0109. . Retrieved 2021/08/28.
• 2、 -. "CANCER TREATMENTS TARGETING CANCER STEM CELLS". Paragraph 0331; 0402-0404; 0468-0469. . Retrieved 2019/11/19.