Technology Process of 12,14-Pentacosadiynoic acid
There total 8 articles about 12,14-Pentacosadiynoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dipyridinium dichromate;
In
N,N-dimethyl-formamide;
Ambient temperature;
DOI:10.1021/jo00025a045
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1) n-butyllithium / 1) THF, -23 deg C, 1 h, 2) THF, HMPA, 2.1) -23 deg C, 30 min., 2.2) RT, 1.5 h
2: 93 percent / 37percent HCl / methanol / Ambient temperature
3: 85 percent / pyridinium dichromate / dimethylformamide / Ambient temperature
With
hydrogenchloride; dipyridinium dichromate; n-butyllithium;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1021/jo00025a045
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 95 percent / phosphorus pentoxide / CH2Cl2 / Ambient temperature
2: 1) CH3Li*LiBr / 1) THF, RT, 3.5 h, 2) THF, HMPA, RT, 30 min
3: KF*2H2O / dimethylformamide / 0.5 h / Ambient temperature
4: 1) n-butyllithium / 1) THF, -23 deg C, 1 h, 2) THF, HMPA, 2.1) -23 deg C, 30 min., 2.2) RT, 1.5 h
5: 93 percent / 37percent HCl / methanol / Ambient temperature
6: 85 percent / pyridinium dichromate / dimethylformamide / Ambient temperature
With
hydrogenchloride; phosphorus pentaoxide; potassium fluoride; dipyridinium dichromate; n-butyllithium; methyllithium lithium bromide;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00025a045