5-Aminolevulinic acid benzyl ester hydrochloride

Base Information

• Chemical Name: 5-Aminolevulinic acid benzyl ester hydrochloride
• CAS No.: 163271-32-7
• Molecular Formula: C₁₂H₁₅NO₃*ClH
• Molecular Weight: 257.717
• Hs Code.: 2922509090
• Mol file: 163271-32-7.mol

Synonyms:Pentanoicacid, 5-amino-4-oxo-, phenylmethyl ester, hydrochloride (9CI);5-Aminolevulinicacid benzyl ester hydrochloride;Benzyl 5-amino-4-oxopentanoate hydrochloride;d-Aminolevulinic acid benzyl esterhydrochloride;

Chemical Property of 5-Aminolevulinic acid benzyl ester hydrochloride

Chemical Property:

• Vapor Pressure: 2.61E-06mmHg at 25°C
• Boiling Point: 385.1 °C at 760 mmHg
• Flash Point: 186.7 °C
• PSA: 69.39000
• LogP: 2.54010

Purity/Quality:

98%Min ^*data from raw suppliers

5-Aminolevulinicacidbenzylesterhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-Aminolevulinic acid benzyl ester, HCl

Technology Process of 5-Aminolevulinic acid benzyl ester hydrochloride

There total 3 articles about 5-Aminolevulinic acid benzyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-aminolevulinic acid hydrochloride (5451-09-2) + benzyl alcohol (100-51-6,185532-71-2) → 5-aminolevulinic acid benzyl ester hydrochloride (163271-32-7)

Guidance literature:

With thionyl chloride; at 60 ℃; for 5h;

DOI:10.1562/0031-8655(2003)078<0481:NAAEPP>2.0.CO;2

Reference yield:

ALA (106-60-5) + benzyl alcohol (100-51-6,185532-71-2) → 5-aminolevulinic acid benzyl ester hydrochloride (163271-32-7)

Guidance literature:

With thionyl chloride; at 60 ℃; for 5h;

DOI:10.1562/0031-8655(2001)074<0721:TEOAAE>2.0.CO;2

Reference yield:

→ 5-aminolevulinic acid benzyl ester hydrochloride (163271-32-7)

Guidance literature:

upstream raw materials:

ALA

benzyl alcohol

5-aminolevulinic acid hydrochloride

Refernces

• 1、 Zhu, Wei,Gao, Ying-Hua,Song, Chun-Hong,Lu, Zhi-Bin,Namulinda, Tabbisa,Han, Yi-Ping,Yan, Yi-Jia,Wang, Lai-Xing,Chen, Zhi-Long. "Synthesis and evaluation of new 5-aminolevulinic acid derivatives as prodrugs of protoporphyrin for photodynamic therapy". . p. 1623 - 1630. Retrieved 2017.
• 2、 -. "Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy". . . Retrieved 2008/06/13.