3-Bromostyrene oxide

Base Information

• Chemical Name: 3-Bromostyrene oxide
• CAS No.: 131567-05-0
• Molecular Formula: C₈H₇BrO
• Molecular Weight: 199.047
• Mol file: 131567-05-0.mol

Synonyms:Benzene,1-bromo-3-(epoxyethyl)- (8CI);(3-Bromophenyl)oxirane;m-Bromostyrene oxide;

Chemical Property of 3-Bromostyrene oxide

Chemical Property:

• Vapor Pressure: 0.0363mmHg at 25°C
• Refractive Index: 1.605
• Boiling Point: 249.4 °C at 760 mmHg
• Flash Point: 98.8 °C
• PSA: 12.53000
• Density: 1.596g/cm³
• LogP: 2.52040

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Bromostyrene oxide

There total 24 articles about 3-Bromostyrene oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-bromostyrene (2039-86-3,25584-47-8) → 2-(3-bromophenyl)oxirane (28022-44-8,131567-05-0)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; at 0 - 20 ℃;

DOI:10.1021/acs.jcim.7b00733

Reference yield: 98.0%

3-bromostyrene (2039-86-3,25584-47-8) → (R)-(+)-(3-bromophenyl)oxirane (691894-14-1,131567-05-0)

Guidance literature:

With P₄₅₀tol-glucose dehydrogenase; In aq. phosphate buffer; ethanol; at 30 ℃; for 5h; enantioselective reaction; Microbiological reaction;

DOI:10.1039/c4cc03491k

Reference yield: 93.0%

2,3'-dibromoacetophenone (18523-22-3) → (R)-(+)-(3-bromophenyl)oxirane (691894-14-1,131567-05-0)

Guidance literature:

With sodium formate; In water; at 25 ℃; enantioselective reaction;

DOI:10.1002/cctc.201700436

upstream raw materials:

3-bromostyrene

m-chloroperoxybenzoic acid

2,3'-dibromoacetophenone

methylenedimethyl sulfurane

Downstream raw materials:

C₁₄H₁₁⁽²⁾HOS

1-(3-Bromophenyl)ethanone

(R)-(-)-1-(3-bromophenyl)ethane-1,2-diol

Refernces

• 1、 Guo, Zheng,Xie, Jinglei,Hu, Tao,Chen, Yunrong,Tao, Houchao,Yang, Xiaoyu. "Kinetic resolution ofN-aryl β-amino alcoholsviaasymmetric aminations of anilines". supporting information. p. 9394 - 9397. Retrieved 2021/09/22.
• 2、 Franssen, Maurice C. R.,Hollmann, Frank,Martínez-Montero, Lía,Paul, Caroline E.,Süss, Philipp,Schallmey, Anett,Tischler, Dirk. "Asymmetric azidohydroxylation of styrene derivatives mediated by a biomimetic styrene monooxygenase enzymatic cascade". . p. 5077 - 5085. Retrieved 2021/08/16.