2-(2-Bromophenyl)furan

Base Information

• Chemical Name: 2-(2-Bromophenyl)furan
• CAS No.: 38527-58-1
• Molecular Formula: C₁₀H₇BrO
• Molecular Weight: 223.069
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID20469493
• Nikkaji Number: J1.809.577G
• Wikidata: Q82297247
• Mol file: 38527-58-1.mol

Synonyms:2-(2-bromophenyl)furan;38527-58-1;Furan,2-(2-bromophenyl)-;(bromophenyl)furan;SCHEMBL5102269;DTXSID20469493;AKOS024093745;MS-22275;CS-0364410;FT-0742240

Chemical Property of 2-(2-Bromophenyl)furan

Chemical Property:

• Vapor Pressure: 0.017mmHg at 25°C
• Refractive Index: 1.576
• Boiling Point: 263.617 °C at 760 mmHg
• Flash Point: 113.232 °C
• PSA: 13.14000
• Density: 1.451 g/cm³
• LogP: 3.70910
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 221.96803
• Heavy Atom Count: 12
• Complexity: 149

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-bromophenyl)furan ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C2=CC=CO2)Br

Technology Process of 2-(2-Bromophenyl)furan

There total 9 articles about 2-(2-Bromophenyl)furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-(2-bromophenyl)-buta-2,3-dien-1-one (196953-04-5) → 1-bromo-2-(furan-2-yl)benzene (38527-58-1)

Guidance literature:

With chloro porphyrinato gold(III); trifluoroacetic acid; In acetone; at 60 ℃; for 0.5h;

DOI:10.1021/ol052696c

Reference yield: 81.0%

furan (110-00-9) + 2-bromobenzenediazonium tetrafluoroborate (10448-07-4) → 1-bromo-2-(furan-2-yl)benzene (38527-58-1)

Guidance literature:

With polyaniline reduced form; In dimethylsulfoxide-d6; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/chem.201501969

Reference yield: 79.0%

furan (110-00-9) + 2-bromoaniline (615-36-1) → 1-bromo-2-(furan-2-yl)benzene (38527-58-1)

Guidance literature:

2-bromoaniline; With tetrafluoroboric acid; tert.-butylnitrite; In ethanol; at 4 - 20 ℃; for 2h;

furan; In dimethyl sulfoxide; at 25 ℃; for 2h; Inert atmosphere; Irradiation;

DOI:10.1039/d0cc01874k

upstream raw materials:

furan

2-bromophenylhydrazine hydrochloride

(2-bromophenyl)boronic acid

2,3-dibromobenzene

Refernces

• 1、 Annes, Sesuraj Babiola,Ramesh, Subburethinam,Saravanan, Subramanian,Saritha, Rajendhiran. "Carbazole based Electron Donor Acceptor (EDA) catalysis for the synthesis of biaryl and aryl-heteroaryl compounds". supporting information. p. 2510 - 2515. Retrieved 2020/04/15.
• 2、 Zorba, Leandros,Kidonakis, Marios,Saridakis, Iakovos,Stratakis, Manolis. "Cycloisomerization of Conjugated Allenones into Furans under Mild Conditions Catalyzed by Ligandless Au Nanoparticles". supporting information. p. 5552 - 5555. Retrieved 2019/08/01.