3,5-Dichloro-4-hydroxybenzenesulfonyl chloride

Base Information

• Chemical Name: 3,5-Dichloro-4-hydroxybenzenesulfonyl chloride
• CAS No.: 13432-81-0
• Molecular Formula: C6H3Cl3O3S
• Molecular Weight: 261.513
• Hs Code.: 2908999090
• European Community (EC) Number: 672-263-5
• DSSTox Substance ID: DTXSID30371073
• Wikidata: Q82158312
• Mol file: 13432-81-0.mol

Synonyms:13432-81-0;3,5-Dichloro-4-hydroxybenzenesulfonyl chloride;3,5-Dichloro-4-Hydroxybenzene-1-Sulfonyl Chloride;3,5-dichloro-4-hydroxybenzenesulphonyl chloride;MFCD00171551;3,5-dichloro-4-hydroxy benzene sulphonyl chloride;3,5-dichloro-4-hydroxy-benzenesulfonyl Chloride;Benzenesulfonyl chloride, 3,5-dichloro-4-hydroxy-;SCHEMBL1056064;DTXSID30371073;AELFLPJWVRGXKU-UHFFFAOYSA-N;BBL100467;STL554261;AKOS005254543;PS-10878;CS-0206233;FT-0636891;EN300-271004;F83011;Benzenesulfonylchloride,3,5-dichloro-4-hydroxy-;3,5-Dichloro-4-Hydroxybenzene-1-SulfonylChloride;J-511289;3,5-Dichloro-4-hydroxybenzenesulphonyl chloride, AldrichCPR

Chemical Property of 3,5-Dichloro-4-hydroxybenzenesulfonyl chloride

Chemical Property:

• Vapor Pressure: 1.91E-05mmHg at 25°C
• Melting Point: 123-125°C
• Refractive Index: 1.611
• Boiling Point: 352.3 °C at 760 mmHg
• Flash Point: 166.8 °C
• PSA: 62.75000
• Density: 1.761g/cm³
• LogP: 3.70730
• Storage Temp.: 2-8°C
• Sensitive.: Moisture Sensitive
• Water Solubility.: Hydrolyzes in water.
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 259.886848
• Heavy Atom Count: 13
• Complexity: 261

Purity/Quality:

98%min ^*data from raw suppliers

3,5-Dichloro-4-hydroxybenzenesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C,Xi
• Statements: 34-36
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1Cl)O)Cl)S(=O)(=O)Cl
• Uses: It is employed in the convergent syntheses involving hydroxyarenesulfonyl chlorides.

Technology Process of 3,5-Dichloro-4-hydroxybenzenesulfonyl chloride

There total 1 articles about 3,5-Dichloro-4-hydroxybenzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3,5-dichloro-4-hydroxybenzene-1-sulfonyl chloride (13432-81-0)

Guidance literature:

2,6-Dichlor-phenol 2, Chlorsulfonsaeure;

Reference yield: 72.0%

3,5-dichloro-4-hydroxybenzene-1-sulfonyl chloride (13432-81-0) → 3,5-dichloro-4-hydroxybenzenesulfinic acid (125927-90-4)

Guidance literature:

With triethylamine; para-thiocresol; In dichloromethane; at -76 ℃; for 0.25h;

DOI:10.1021/jo00295a062

Reference yield: 64.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 3,5-dichloro-4-hydroxybenzene-1-sulfonyl chloride (13432-81-0) → 3,5-dichloro-4-methoxybenzenesulfonyl chloride (35517-53-4)

Guidance literature:

In diethyl ether; at 25 ℃;

DOI:10.1021/jo00295a062

Downstream raw materials:

3,5-dichloro-4-methoxybenzenesulfonyl chloride

3,5-dichloro-4-hydroxybenzenesulfinic acid

Sodium; 3,5-dichloro-4-hydroxy-benzenesulfonate

3,5-dichloro-4-hydroxybenzene sulfonic acid