2,4,6-Trimethoxyphenylacetic acid

Base Information

• Chemical Name: 2,4,6-Trimethoxyphenylacetic acid
• CAS No.: 104397-80-0
• Molecular Formula: C11H14O5
• Molecular Weight: 226.229
• Hs Code.: 2918990090
• European Community (EC) Number: 623-776-8
• DSSTox Substance ID: DTXSID10412736
• Mol file: 104397-80-0.mol

Synonyms:2,4,6-Trimethoxyphenylacetic acid;104397-80-0;2-(2,4,6-trimethoxyphenyl)acetic Acid;Benzeneacetic acid,2,4,6-trimethoxy-;2,4,6-Trimethoxyphenylessig;SCHEMBL1599400;DTXSID10412736;XVJDJIVBWDQELV-UHFFFAOYSA-N;AKOS015911958;CS-0345728;FT-0600538;2,4,6-Trimethoxyphenylacetic acid, >=97.0%;2-(2,4-dimethoxyphenyl)-2-methoxy-acetic acid;EN300-1832737;A800977;J-001166

Chemical Property of 2,4,6-Trimethoxyphenylacetic acid

Chemical Property:

• Vapor Pressure: 2.49E-06mmHg at 25°C
• Melting Point: 182-185 °C
• Refractive Index: 1.519
• Boiling Point: 376.3 °C at 760 mmHg
• Flash Point: 145.1 °C
• PSA: 64.99000
• Density: 1.197 g/cm³
• LogP: 1.33950
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 226.08412354
• Heavy Atom Count: 16
• Complexity: 216

Purity/Quality:

98%min ^*data from raw suppliers

2,4,6-Trimethoxyphenylacetic acid ≥97.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C(=C1)OC)CC(=O)O)OC

Technology Process of 2,4,6-Trimethoxyphenylacetic acid

There total 3 articles about 2,4,6-Trimethoxyphenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (2,4,6-trimethoxy-phenyl)-acetic acid (104397-80-0)

Guidance literature:

With dihydrogen peroxide;

Reference yield:

(2,4,6-trimethoxy-phenyl)-pyruvic acid (105338-31-6) + dihydrogen peroxide (7722-84-1) → (2,4,6-trimethoxy-phenyl)-acetic acid (104397-80-0)

Guidance literature:

Reference yield:

→ Sulfamic acid [2,4,6-trimethoxyphenyl(acetyl)]-2,6-bis(1-methylethyl)-phenyl ester + (2,4,6-trimethoxy-phenyl)-acetic acid (104397-80-0)

Guidance literature:

upstream raw materials:

(2,4,6-trimethoxy-phenyl)-pyruvic acid

dihydrogen peroxide

Downstream raw materials:

3,4,2',4',6'-pentamethoxy-deoxybenzoin

3-[2-(2,4,6-Trimethoxy-phenyl)-acetylamino]-benzoic acid

3-[2-(2,4,6-Trimethoxy-phenyl)-acetylamino]-benzoic acid methyl ester

4-((Z)-3-chloro-2,4,6-trimethoxy-benzylidene)-2-phenyl-4H-oxazol-5-one

Refernces