1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

Base Information Edit

Chemical Name:1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
CAS No.:5654-97-7
Molecular Formula:C7H6 N2 O
Molecular Weight:134.137
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10551472
Nikkaji Number:J81.071A
Wikidata:Q72444339
Mol file:5654-97-7.mol

Synonyms:5654-97-7;1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one;1H-pyrrolo[2,3-b]pyridin-2(3H)-one;7-AZAOXINDOLE;1,3-dihydropyrrolo[2,3-b]pyridin-2-one;1,3-Dihydro-2H-pyrrolo[2,3-b]pyridine-2-one;1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one;MFCD07367951;1,3-Dihydro-2H-pyrrolo[2.3-b]pyridine-2-one;1,3-dihydro-2h-pyrrolo(2,3-b)pyridin-2-one;Silvercarbonate;2H-PYRROLO[2,3-B]PYRIDIN-2-ONE, 1,3-DIHYDRO-;7-AZA-2-OXINDOLE;1,3-DIHYDROPYRROLO[2,3-B]PYRIDINE-2-ONE;SCHEMBL578594;DTXSID10551472;ZXSQEZNORDWBGZ-UHFFFAOYSA-N;AKOS006287010;AC-5052;CS-W019704;PB29419;SY008090;1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one;AM20061330;1,2-dihydro-3H-pyrrolo[2,3-b]pyridin-2-one;A831090;J-504754;1 pound not3-DIHYDRO-2H-PYRROLO[2 pound not3-B]PYRIDINE-2-ONE

Suppliers and Price of 1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Azaoxindole
1g
$ 1055.00

SynQuest Laboratories
1H,2H,3H-Pyrrolo[2,3-b]pyridin-2-one 97.0%
25 g
$ 1290.00

SynQuest Laboratories
1H,2H,3H-Pyrrolo[2,3-b]pyridin-2-one 97.0%
250 mg
$ 115.00

SynQuest Laboratories
1H,2H,3H-Pyrrolo[2,3-b]pyridin-2-one 97.0%
1 g
$ 290.00

SynQuest Laboratories
1H,2H,3H-Pyrrolo[2,3-b]pyridin-2-one 97.0%
5 g
$ 790.00

Matrix Scientific
1,3-Dihydropyrrolo[2,3-b]pyridin-2-one >95%
25g
$ 825.00

Matrix Scientific
1,3-Dihydropyrrolo[2,3-b]pyridin-2-one >95%
1g
$ 38.00

Matrix Scientific
1,3-Dihydropyrrolo[2,3-b]pyridin-2-one >95%
5g
$ 274.00

Labseeker
1,3-DIHYDRO-2H-PYRROLO[2.3-B]PYRIDINE-2-ONE 95
1g
$ 1217.00

Crysdot
1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one 98%
1g
$ 71.00

Total 61 raw suppliers

Chemical Property of 1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:175 °C
Refractive Index:1.594
Boiling Point:362.474 °C at 760 mmHg
PKA:3.42±0.20(Predicted)
Flash Point:173.019 °C
PSA：41.99000
Density:1.286 g/cm³
LogP:0.71420
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:134.048012819
Heavy Atom Count:10
Complexity:158

Purity/Quality:

98% ^*data from raw suppliers

7-Azaoxindole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(NC1=O)N=CC=C2
Uses 1,3-DIHYDRO-2H-PYRROLO[2,3-B]PYRIDINE-2-ONE is used for preparation of 3-(anilinomethylene)oxindoles and analogs as protein tyrosine kinase and protein serine/threonine kinase inhibitors.

Technology Process of 1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

There total 27 articles about 1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 113423-51-1
3,3-Dibromo-1,3-dihydro-2H-pyrrolo[2,3-b]-pyridin-2-one

: 5654-97-7
7-azaoxindole

Guidance literature:: With acetic acid; zinc; In acetonitrile;

Reference yield: 83.0%

: C₁₃H₁₄N₄O₂S

: 13939-06-5,199620-15-0
molybdenum hexacarbonyl

: 5654-97-7
7-azaoxindole

Guidance literature:: With tetraethylammonium bromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,4-dioxane; at 20 - 110 ℃; for 1h;
DOI:10.1016/j.tetlet.2015.09.123