2,6-Dimethylpyridin-3-ylboronic acid

Base Information

• Chemical Name: 2,6-Dimethylpyridin-3-ylboronic acid
• CAS No.: 693774-55-9
• Molecular Formula: C7H10BNO2
• Molecular Weight: 150.973
• Hs Code.: 2933399990
• European Community (EC) Number: 851-150-6
• DSSTox Substance ID: DTXSID60376733
• Wikidata: Q82165641
• Mol file: 693774-55-9.mol

Synonyms:693774-55-9;2,6-Dimethylpyridin-3-ylboronic acid;2,6-DIMETHYLPYRIDINE-3-BORONIC ACID;(2,6-dimethylpyridin-3-yl)boronic Acid;2,6-Domethylpyridine-3-boronic acid;MFCD07437925;2,6-Dimethylpyridine-3-boronicacid;2,6-Dimethyl-pyridine-3-boronic acid;Boronic acid, (2,6-dimethyl-3-pyridinyl)-;(2,6-dimethyl-3-pyridinyl)boronic acid;SCHEMBL489376;AMY8036;DTXSID60376733;OZGKXVIJOMDZCP-UHFFFAOYSA-N;2,6-Dimethylpyridin-3-ylboronicacid;AKOS006285112;AB41961;CS-W020654;FD10078;AC-33301;DS-12835;SY029371;B-(2,6-Dimethyl-3-pyridinyl)-boronicacid;B-(2,6-Dimethyl-3-pyridinyl)boronic acid;FT-0646484;EN300-316361;2,6-dimethyl-pyridine-3-boronic acid, AldrichCPR;A836459

Chemical Property of 2,6-Dimethylpyridin-3-ylboronic acid

Chemical Property:

• Vapor Pressure: 0.000675mmHg at 25°C
• Refractive Index: 1.522
• Boiling Point: 295.8 °C at 760 mmHg
• PKA: 4.35±0.58(Predicted)
• Flash Point: 132.7 °C
• PSA: 53.35000
• Density: 1.14 g/cm³
• LogP: -0.62180
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 151.0804587
• Heavy Atom Count: 11
• Complexity: 132

Purity/Quality:

98%min ^*data from raw suppliers

2,6-Dimethylpyridine-3-boronicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: B(C1=C(N=C(C=C1)C)C)(O)O
• Uses: 2,6-Dimethylpyridine-3-boronic acid

Technology Process of 2,6-Dimethylpyridin-3-ylboronic acid

There total 1 articles about 2,6-Dimethylpyridin-3-ylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (2,6-dimethylpyridin-3-yl)boronic acid (693774-55-9) + 2,6-dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (693774-10-6)

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; at 120 ℃; for 2h; Inert atmosphere; Sealed tube;

Reference yield: 78.0%

(2,6-dimethylpyridin-3-yl)boronic acid (693774-55-9) + C33H20BrN5 → C40H28N6

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; toluene; at 100 ℃; for 24h; Schlenk technique; Inert atmosphere;

Reference yield: 71.2%

(2,6-dimethylpyridin-3-yl)boronic acid (693774-55-9) + C25H13BrINO → C32H21BrN2O

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; water; toluene; at 80 ℃; for 12h;

Downstream raw materials:

methyl N-[[5-[3-(2,6-dimethyl-3-pyridinyl)-1H-pyrazol-1-yl]-2-methylphenyl]methyl]carbamate

Refernces