4-Amino-n-(4-aminophenyl)benzenesulfonamide

Base Information

• Chemical Name: 4-Amino-n-(4-aminophenyl)benzenesulfonamide
• CAS No.: 16803-97-7
• Molecular Formula: C12H13N3O2S
• Molecular Weight: 263.32
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID70884935
• Nikkaji Number: J236.855B
• Wikidata: Q72462664
• ChEMBL ID: CHEMBL167411
• Mol file: 16803-97-7.mol

Synonyms:4-amino-n-(4-aminophenyl)benzenesulfonamide;16803-97-7;4,4'-Diaminobenzenesulphanilide;Benzenesulfonamide, 4-amino-N-(4-aminophenyl)-;4,4-Diaminobenzenesulphanilide;4,4'-Diaminobenzenesulfonanilide;Cambridge id 5401608;Oprea1_213884;Oprea1_386092;SCHEMBL540915;CHEMBL167411;4,4'-diaminodiphenyl sulfonamide;DTXSID70884935;4,4'-diaminobenzene sulfonanilide;MFCD00082174;AKOS003616653;SDCCGMLS-0065463.P001;AS-15554;CS-0157464;FT-0623030;D82228;4-amino-N-(4-aminophenyl)benzene-1-sulfonamide;AB00084021-01;SR-01000207877;SR-01000207877-1;W-107902;Z56877089

Chemical Property of 4-Amino-n-(4-aminophenyl)benzenesulfonamide

Chemical Property:

• Vapor Pressure: 0Pa at 25℃
• Melting Point: 138 °C
• Boiling Point: 511.3 °C at 760 mmHg
• PKA: 10.18±0.10(Predicted)
• Flash Point: 263 °C
• PSA: 106.59000
• Density: 1.438 g/cm³
• LogP: 4.09510
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Water Solubility.: 13.41g/L at 25℃
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 263.07284784
• Heavy Atom Count: 18
• Complexity: 350

Purity/Quality:

99% ^*data from raw suppliers

4,4-Diaminobenzenesulphanilide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1N)NS(=O)(=O)C2=CC=C(C=C2)N
• Uses: 4,4-Diaminobenzenesulphanilide can be used as macromolecule black hair dye.

Technology Process of 4-Amino-n-(4-aminophenyl)benzenesulfonamide

There total 17 articles about 4-Amino-n-(4-aminophenyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-acetylaminobenzenesulfonyl chloride (121-60-8) → p-aminobenzenesulphonamido-4-aniline (16803-97-7)

Guidance literature:

Multi-step reaction with 3 steps

1: acetone; pyridine

2: aq.-ethanolic hydrochloric acid

3: aqueous sodium carbonate; sodium dithionite

With pyridine; hydrogenchloride; sodium dithionite; sodium carbonate; acetone;

DOI:10.1021/ja01872a020

Reference yield:

N-acetyl-sulfanilic acid-(4-amino-anilide) (22941-28-2) → p-aminobenzenesulphonamido-4-aniline (16803-97-7)

Guidance literature:

With hydrogenchloride;

Reference yield:

4-amino-N-(4-nitrophenyl)-benzenesulfonamide (6829-82-9) → p-aminobenzenesulphonamido-4-aniline (16803-97-7)

Guidance literature:

With nickel; Hydrogenation;

upstream raw materials:

N-(p-Nitrophenyl)-p-chlorobenzenesulfonamide

4-amino-N-(4-nitrophenyl)-benzenesulfonamide

N-acetyl-sulfanilic acid-(4-amino-anilide)

N-acetyl-sulfanilic acid-(4-acetylamino-anilide)

Downstream raw materials:

trans-iodobis(diphenylglyoximato)(p-aminobenzenesulphonamido-4-aniline)cobalt(III)

trans-chlorobis(diphenylglyoximato)(p.aminobenzenesulphonamido-4-aniline)cobalt(III) monohydrate

N-(4-aminophenyl)-4-((4Z)-4-[(6-bromo-2-chloro-3-quinolinyl)-methylene]-5-oxo-2-phenyl-4,5-dihydro-1H-imidazol-1-yl)benzenesulfonamide

N-(4-aminophenyl)-4-{(4Z)-4-[(2-chloro-7-methyl-3-quinolinyl)methylene]-5-oxo-2-phenyl-4,5-dihydro-1H-imidazol-1-yl}benzenesulfonamide