Technology Process of 4-chloro-2-iodo-1-(propan-2-yl)benzene
There total 3 articles about 4-chloro-2-iodo-1-(propan-2-yl)benzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
5-chloro-2-isopropylaniline;
With
toluene-4-sulfonic acid; sodium nitrite;
In
water;
for 0.166667h;
With
potassium iodide;
In
water;
for 0.333333h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: nitric acid / sulfuric acid / 1 h / -5 - 10 °C
1.2: pH 7
2.1: hydrogenchloride; sodium nitrite / water / 1.5 h / 0 °C
2.2: 2 h / 20 - 80 °C
3.1: hydrazine hydrate; iron(III) chloride / methanol / 7 h / Reflux
4.1: toluene-4-sulfonic acid; sodium nitrite / water / 0.17 h
4.2: 0.33 h
With
hydrogenchloride; iron(III) chloride; nitric acid; toluene-4-sulfonic acid; hydrazine hydrate; sodium nitrite;
sulfuric acid;
In
methanol; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrazine hydrate; iron(III) chloride / methanol / 7 h / Reflux
2.1: toluene-4-sulfonic acid; sodium nitrite / water / 0.17 h
2.2: 0.33 h
With
iron(III) chloride; toluene-4-sulfonic acid; hydrazine hydrate; sodium nitrite;
In
methanol; water;
