Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

4-Amino-2-chloro-6,7-dimethoxyquinazoline

Base Information Edit
  • Chemical Name:4-Amino-2-chloro-6,7-dimethoxyquinazoline
  • CAS No.:23680-84-4
  • Molecular Formula:C10H10ClN3O2
  • Molecular Weight:239.661
  • Hs Code.:29339900
  • European Community (EC) Number:245-821-7
  • UNII:FG7Z4T71Y4
  • DSSTox Substance ID:DTXSID3057694
  • Nikkaji Number:J86.521D
  • Wikidata:Q27277971
  • ChEMBL ID:CHEMBL3561187
  • Mol file:23680-84-4.mol
4-Amino-2-chloro-6,7-dimethoxyquinazoline

Synonyms:23680-84-4;4-Amino-2-chloro-6,7-dimethoxyquinazoline;2-Chloro-6,7-dimethoxyquinazolin-4-amine;2-Chloro-4-amino-6,7-dimethoxyquinazoline;2-Chloro-6,7-dimethoxy-4-quinazolinamine;4-Quinazolinamine, 2-chloro-6,7-dimethoxy-;2680-84-4;MFCD00051734;UNII-FG7Z4T71Y4;FG7Z4T71Y4;2-chloro-4-amino-6,7-dimethoxy quinazoline;2-chloro-4-amino-6,7-dimethoxy-quinazoline;DTXSID3057694;EINECS 245-821-7;EC 245-821-7;SR-01000197509;Prazosin impurity A;Doxazosin impurity F;Terazosin impurity A;BIDD:GT0452;SCHEMBL611438;10-PROPOXY-DECANOICACID;CHEMBL3561187;DTXCID4031483;(E/Z)-Trelnarizine Dihydrochloride;BCP28790;Tox21_113801;STK503641;AKOS000264944;AC-5334;PS-3289;4amino-2-chloro6,7-dimethoxyquinazoline;NCGC00253677-01;4-amino-2chloro-6,7-dimethoxyquinazoline;SY008892;4-AMino-2-chloro-6,7-diMethoxyquinazolin;2-chloro-6,7-dimethoxy quinazolin-4-amine;2-chloro-6,7-dimethoxy-4-aminoquinazoline;2-chloro-6,7-dimethoxyquinazolin-4-ylamine;4-amino-2chloro-6,7-dimethoxy quinazoline;CAS-23680-84-4;2-chloro-4-amino-6,7-dimethoxyquin-azoline;2-Chloro-6,7-dimethoxy-4-quinazolinamine #;4-Amino-2-chloro-6,7-bismethoxyquinazoline;4-amino-2-chloro-6,7-dimethoxy quinazoline;4-amino-2-chloro-6,7-dimethoxy-quinazoline;AM20030412;BB 0257419;CS-0127991;FT-0620860;EN300-66004;4-Amino-2-chloro-6,7-dimethoxyquinazoline, 95%;AE-848/31926053;DOXAZOSIN MESILATE IMPURITY F [EP IMPURITY];SR-01000197509-1;SR-01000197509-2;W-107385;PRAZOSIN HYDROCHLORIDE IMPURITY A [EP IMPURITY];Q27277971;QUINAZOLINE, 4-AMINO-2-CHLORO-6,7-DIMETHOXY-;ALFUZOSIN HYDROCHLORIDE IMPURITY B [EP IMPURITY];Z1033088242;Doxazosin impurity F, European Pharmacopoeia (EP) Reference Standard;TERAZOSIN HYDROCHLORIDE DIHYDRATE IMPURITY A [EP IMPURITY];Terazosin impurity A, European Pharmacopoeia (EP) Reference Standard;4-Amino-2-chloro-6,7-dimethoxyquinazoline, puriss., >=99.0% (HPLC)

Suppliers and Price of 4-Amino-2-chloro-6,7-dimethoxyquinazoline
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • 4-Amino-2-chloro-6,7-dimethoxyquinazoline
  • 10g
  • $ 340.00
  • TRC
  • 4-Amino-2-chloro-6,7-dimethoxyquinazoline
  • 50g
  • $ 240.00
  • TCI Chemical
  • 4-Amino-2-chloro-6,7-dimethoxyquinazoline >98.0%(HPLC)(N)
  • 25g
  • $ 151.00
  • TCI Chemical
  • 4-Amino-2-chloro-6,7-dimethoxyquinazoline >98.0%(HPLC)(N)
  • 5g
  • $ 51.00
  • SynQuest Laboratories
  • 4-Amino-2-chloro-6,7-dimethoxyquinazoline
  • 5 g
  • $ 16.00
  • SynQuest Laboratories
  • 4-Amino-2-chloro-6,7-dimethoxyquinazoline
  • 25 g
  • $ 28.00
  • Sigma-Aldrich
  • Doxazosin Related Compound C United States Pharmacopeia (USP) Reference Standard
  • 20mg
  • $ 1260.00
  • Sigma-Aldrich
  • Doxazosin impurity F European Pharmacopoeia (EP) Reference Standard
  • y0000552
  • $ 190.00
  • Sigma-Aldrich
  • Terazosin impurity A European Pharmacopoeia (EP) Reference Standard
  • y0000622
  • $ 190.00
  • Sigma-Aldrich
  • 4-Amino-2-chloro-6,7-dimethoxyquinazoline 95%
  • 25g
  • $ 120.00
Total 168 raw suppliers
Chemical Property of 4-Amino-2-chloro-6,7-dimethoxyquinazoline Edit
Chemical Property:
  • Appearance/Colour:off-white solid 
  • Vapor Pressure:8.63E-06mmHg at 25°C 
  • Melting Point:262-268 °C (dec.)(lit.) 
  • Refractive Index:1.649 
  • Boiling Point:374 °C at 760 mmHg 
  • PKA:4.35±0.30(Predicted) 
  • Flash Point:180 °C 
  • PSA:70.26000 
  • Density:1.391 g/cm3 
  • LogP:2.46380 
  • Storage Temp.:2-8°C 
  • Solubility.:DMSO (Sparingly, Heated), Methanol (Slightly, Heated) 
  • Water Solubility.:1.418g/L at 25℃ 
  • XLogP3:2.2
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:2
  • Exact Mass:239.0461543
  • Heavy Atom Count:16
  • Complexity:244
Purity/Quality:

99% *data from raw suppliers

4-Amino-2-chloro-6,7-dimethoxyquinazoline *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi,HarmfulXn 
  • Hazard Codes:Xi,Xn 
  • Statements: 36/37/38-20/21/22 
  • Safety Statements: 26-36-37/39 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:COC1=C(C=C2C(=C1)C(=NC(=N2)Cl)N)OC
  • Uses Intermediate in the production on Terazosin.
Technology Process of 4-Amino-2-chloro-6,7-dimethoxyquinazoline

There total 16 articles about 4-Amino-2-chloro-6,7-dimethoxyquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With trichlorophosphate; at 25 - 70 ℃; for 1h;
Guidance literature:
With ammonia; In tetrahydrofuran; at 20 ℃; for 44h;
DOI:10.1021/jo026217o
Guidance literature:
3-cyano-1-(3,4-dimethoxyphenyl)urea; With phosphorus pentachloride; trichlorophosphate; In water; toluene; at 10 ℃; for 3.5h; Reflux;
With formic acid; In water; toluene; for 0.5h; Reflux;
With triethylamine; In ethanol; for 0.5h; Reflux;
Post RFQ for Price