[[((1,1-dimethylethyl)amino)sulfonyl]methyl]benzoic acid methyl ester

Base Information

• Chemical Name: [[((1,1-dimethylethyl)amino)sulfonyl]methyl]benzoic acid methyl ester
• CAS No.: 415916-11-9
• Molecular Formula: C₁₃H₁₉NO₄S
• Molecular Weight: 285.364
• Mol file: 415916-11-9.mol

Synonyms:[[((1,1-dimethylethyl)amino)sulfonyl]methyl]benzoic acid methyl ester

Chemical Property of [[((1,1-dimethylethyl)amino)sulfonyl]methyl]benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [[((1,1-dimethylethyl)amino)sulfonyl]methyl]benzoic acid methyl ester

There total 3 articles about [[((1,1-dimethylethyl)amino)sulfonyl]methyl]benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.99%

tert-butylamine (75-64-9) + 2-(Chlorosulfonylmethyl)benzoic acid methyl ester (103342-27-4) → [[((1,1-dimethylethyl)amino)sulfonyl]methyl]benzoic acid methyl ester (415916-11-9)

Guidance literature:

In ethyl acetate; at -5 - 20 ℃; for 4.3h; Temperature;

Reference yield:

o-(chloromethyl)benzoic acid methyl ester (34040-62-5) → [[((1,1-dimethylethyl)amino)sulfonyl]methyl]benzoic acid methyl ester (415916-11-9)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol / 18 h / Reflux

2: water; chlorine / dichloromethane / 1.5 h / 1 °C

3: ethyl acetate / 4.3 h / -5 - 20 °C

With water; chlorine; In methanol; dichloromethane; ethyl acetate;

Reference yield:

methyl 2-((carbamimidoylthio)methyl)benzoate hydrochloride → [[((1,1-dimethylethyl)amino)sulfonyl]methyl]benzoic acid methyl ester (415916-11-9)

Guidance literature:

Multi-step reaction with 2 steps

1: water; chlorine / dichloromethane / 1.5 h / 1 °C

2: ethyl acetate / 4.3 h / -5 - 20 °C

With water; chlorine; In dichloromethane; ethyl acetate;

upstream raw materials:

tert-butylamine

2-(Chlorosulfonylmethyl)benzoic acid methyl ester

o-(chloromethyl)benzoic acid methyl ester

Downstream raw materials:

2-(tert-butylsulfamoyl-methyl)-benzoic acid 5-carboxy-pentyl ester

2-sulfamoylmethyl-benzoic acid 5-carboxy-pentyl ester

methyl 2-[(aminosulfonyl)methyl]benzoate

Refernces

• 1、 Lee, Jae Koo,Ahn, Ki Chang,Park, Oee Sook,Ko, Yong Kwan,Kim, Dae-Whang. "Development of an immunoassay for the residues of the herbicide bensulfuron-methyl.". . p. 1791 - 1803. Retrieved 2007/10/03.