Technology Process of N-trifluoro-2-[2,5-dimethoxy-4-(4-phenylbutyl)phenyl]-1-aminoethane
There total 4 articles about N-trifluoro-2-[2,5-dimethoxy-4-(4-phenylbutyl)phenyl]-1-aminoethane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 92 percent / 0 °C
2: 58 percent / ICl; NaI; 0.1 N NaOH / acetic acid / 20 °C
3: 65 percent / pyridine / 120 °C
4: 65 percent / H2 / 10 percent Pd/C / methanol / 4 h / 2068.59 Torr
With
pyridine; sodium hydroxide; hydrogen; Iodine monochloride; sodium iodide;
palladium on activated charcoal;
In
methanol; acetic acid;
1: Acetylation / 2: Iodination / 3: Substitution / 4: Catalytic hydrogenation;
DOI:10.1021/jm9906062
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 65 percent / pyridine / 120 °C
2: 65 percent / H2 / 10 percent Pd/C / methanol / 4 h / 2068.59 Torr
With
pyridine; hydrogen;
palladium on activated charcoal;
In
methanol;
1: Substitution / 2: Catalytic hydrogenation;
DOI:10.1021/jm9906062
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 65 percent / pyridine / 120 °C
2: 65 percent / H2 / 10 percent Pd/C / methanol / 4 h / 2068.59 Torr
With
pyridine; hydrogen;
palladium on activated charcoal;
In
methanol;
1: Substitution / 2: Catalytic hydrogenation;
DOI:10.1021/jm9906062