N-Isopropylacrylamide

Base Information Edit

Chemical Name:N-Isopropylacrylamide
CAS No.:2210-25-5
Deprecated CAS:1254182-74-5,1622299-95-9,2083612-24-0
Molecular Formula:C6H11NO
Molecular Weight:113.159
Hs Code.:29241990
European Community (EC) Number:218-638-5
NSC Number:11448
UNII:B7GFF17L9U
DSSTox Substance ID:DTXSID0033754
Nikkaji Number:J55.124D
Wikidata:Q21012199
ChEMBL ID:CHEMBL1527236
Mol file:2210-25-5.mol

Synonyms:N-isopropylacrylamide

Suppliers and Price of N-Isopropylacrylamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Isopropylacrylamide
5g
$ 60.00

TCI Chemical
N-Isopropylacrylamide (stabilized with MEHQ) >98.0%(GC)
25g
$ 54.00

TCI Chemical
N-Isopropylacrylamide (stabilized with MEHQ) >98.0%(GC)
100g
$ 108.00

TCI Chemical
N-Isopropylacrylamide (stabilized with MEHQ) >98.0%(GC)
500g
$ 235.00

Sigma-Aldrich
N-Isopropylacrylamide ≥99%
25g
$ 144.00

Sigma-Aldrich
N-Isopropylacrylamide 97%
50g
$ 135.00

Sigma-Aldrich
N-Isopropylacrylamide ≥99%
5g
$ 42.70

Sigma-Aldrich
N-Isopropylacrylamide 97%
10g
$ 38.50

Frontier Specialty Chemicals
N-Isopropylacrylamide,99%,stabilizedwith500ppmMEHQ
25g
$ 83.00

Frontier Specialty Chemicals
N-Isopropylacrylamide,99%,stabilizedwith500ppmMEHQ
100g
$ 196.00

Total 132 raw suppliers

Chemical Property of N-Isopropylacrylamide Edit

Chemical Property:

Appearance/Colour:white to light yellow crystalline powder
Vapor Pressure:0.076mmHg at 25°C
Melting Point:60-63 °C(lit.)
Refractive Index:1.445
Boiling Point:225.074 °C at 760 mmHg
PKA:14.83±0.46(Predicted)
Flash Point:119.664 °C
PSA：29.10000
Density:0.877 g/cm³
LogP:1.08790
Storage Temp.:0-6°C
Water Solubility.:Slightly soluble in water.
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:113.084063974
Heavy Atom Count:8
Complexity:96.7

Purity/Quality:

99.8 % ^*data from raw suppliers

N-Isopropylacrylamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Nitrogen Compounds -> Other Nitrogen Compounds
Canonical SMILES:CC(C)NC(=O)C=C
Description N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature-based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST).
Uses NIPAM can be used to prepare poly(NIPAM) for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration. Binders in textiles, paper, adhesives, detergents, cosmetics.N-Isopropylacrylamide is used to produce poly(N-isopropylacrylamide) (pNIPA, pNIPAAm, pNIPAA or pNIPAm) thermo sensitive polymer- or copolymer-based hydrogels. Polymers that contain NIPAM shrink dramatically above 33°C. Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.

Technology Process of N-Isopropylacrylamide

There total 16 articles about N-Isopropylacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%