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N-Isopropylacrylamide

Base Information Edit
  • Chemical Name:N-Isopropylacrylamide
  • CAS No.:2210-25-5
  • Deprecated CAS:1254182-74-5,1622299-95-9,2083612-24-0
  • Molecular Formula:C6H11NO
  • Molecular Weight:113.159
  • Hs Code.:29241990
  • European Community (EC) Number:218-638-5
  • NSC Number:11448
  • UNII:B7GFF17L9U
  • DSSTox Substance ID:DTXSID0033754
  • Nikkaji Number:J55.124D
  • Wikidata:Q21012199
  • ChEMBL ID:CHEMBL1527236
  • Mol file:2210-25-5.mol
N-Isopropylacrylamide

Synonyms:N-isopropylacrylamide

Suppliers and Price of N-Isopropylacrylamide
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • N-Isopropylacrylamide
  • 5g
  • $ 60.00
  • TCI Chemical
  • N-Isopropylacrylamide (stabilized with MEHQ) >98.0%(GC)
  • 25g
  • $ 54.00
  • TCI Chemical
  • N-Isopropylacrylamide (stabilized with MEHQ) >98.0%(GC)
  • 100g
  • $ 108.00
  • TCI Chemical
  • N-Isopropylacrylamide (stabilized with MEHQ) >98.0%(GC)
  • 500g
  • $ 235.00
  • Sigma-Aldrich
  • N-Isopropylacrylamide ≥99%
  • 25g
  • $ 144.00
  • Sigma-Aldrich
  • N-Isopropylacrylamide 97%
  • 50g
  • $ 135.00
  • Sigma-Aldrich
  • N-Isopropylacrylamide ≥99%
  • 5g
  • $ 42.70
  • Sigma-Aldrich
  • N-Isopropylacrylamide 97%
  • 10g
  • $ 38.50
  • Frontier Specialty Chemicals
  • N-Isopropylacrylamide,99%,stabilizedwith500ppmMEHQ
  • 25g
  • $ 83.00
  • Frontier Specialty Chemicals
  • N-Isopropylacrylamide,99%,stabilizedwith500ppmMEHQ
  • 100g
  • $ 196.00
Total 132 raw suppliers
Chemical Property of N-Isopropylacrylamide Edit
Chemical Property:
  • Appearance/Colour:white to light yellow crystalline powder 
  • Vapor Pressure:0.076mmHg at 25°C 
  • Melting Point:60-63 °C(lit.) 
  • Refractive Index:1.445 
  • Boiling Point:225.074 °C at 760 mmHg 
  • PKA:14.83±0.46(Predicted) 
  • Flash Point:119.664 °C 
  • PSA:29.10000 
  • Density:0.877 g/cm3 
  • LogP:1.08790 
  • Storage Temp.:0-6°C 
  • Water Solubility.:Slightly soluble in water. 
  • XLogP3:0.9
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:1
  • Rotatable Bond Count:2
  • Exact Mass:113.084063974
  • Heavy Atom Count:8
  • Complexity:96.7
Purity/Quality:

99.8 % *data from raw suppliers

N-Isopropylacrylamide *data from reagent suppliers

Safty Information:
  • Pictogram(s): HarmfulXn 
  • Hazard Codes:Xn 
  • Statements: 22-36-36/37/38 
  • Safety Statements: 26-36/37/39 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Chemical Classes:Nitrogen Compounds -> Other Nitrogen Compounds
  • Canonical SMILES:CC(C)NC(=O)C=C
  • Description N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature-based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST).
  • Uses NIPAM can be used to prepare poly(NIPAM) for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration. Binders in textiles, paper, adhesives, detergents, cosmetics.N-Isopropylacrylamide is used to produce poly(N-isopropylacrylamide) (pNIPA, pNIPAAm, pNIPAA or pNIPAm) thermo sensitive polymer- or copolymer-based hydrogels. Polymers that contain NIPAM shrink dramatically above 33°C. Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.
Technology Process of N-Isopropylacrylamide

There total 16 articles about N-Isopropylacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With 10H-phenothiazine; copper(II) bis(trifluoromethanesulfonate); at 140 ℃; for 8h; Inert atmosphere;
Guidance literature:
H-ZSM-5; at 149.85 ℃; for 24h; Further Variations:; Catalysts; Product distribution;
DOI:10.1246/cl.1999.799
Guidance literature:
With 4-methoxy-phenol; lithium tert-butoxide; In glycerol; at 230 ℃; Pyrolysis;
Refernces Edit
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