Sudan II

Base Information

• Chemical Name: Sudan II
• CAS No.: 3118-97-6
• Molecular Formula: C18H16N2O
• Molecular Weight: 276.338
• Hs Code.: 32129000
• European Community (EC) Number: 221-490-4,634-847-8
• NSC Number: 10457
• UNII: 8C1M5O3ECT
• DSSTox Substance ID: DTXSID5040706,DTXSID80859795
• Nikkaji Number: J3.714A
• Wikipedia: Sudan_II
• Wikidata: Q15098649
• ChEMBL ID: CHEMBL1552233
• Mol file: 3118-97-6.mol

Synonyms:Sudan II;sudan red

Chemical Property of Sudan II

Chemical Property:

• Appearance/Colour: Red to orange-brownish powder
• Vapor Pressure: 1.38E-07mmHg at 25°C
• Melting Point: 156-158 °C
• Refractive Index: 1.615
• Boiling Point: 429.6 °C at 760 mmHg
• PKA: 13.52±0.50(Predicted)
• Flash Point: 213.6 °C
• PSA: 44.95000
• Density: 1.14 g/cm³
• LogP: 5.57760
• Storage Temp.: Hygroscopic, Refrigerator, Under inert atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Ethyl Acetate (Slight
• Water Solubility.: 54.45μg/L at 25℃
• XLogP3: 5.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 276.126263138
• Heavy Atom Count: 21
• Complexity: 370

Purity/Quality:

99.9% ^*data from raw suppliers

Solvent Orange 7 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Dyes -> Azo Dyes
• Canonical SMILES: CC1=CC(=C(C=C1)N=NC2=C(C=CC3=CC=CC=C32)O)C
• Uses: Sudan II is a fat soluble red synthetic azo dye. Sudan II is reduced to potentially carcinogenic aromatic amines by human intestinal bacteria. Dyes and metabolites, Environmental Testing.

Technology Process of Sudan II

There total 10 articles about Sudan II which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2,4-Xylidine (95-68-1) + β-naphthol (135-19-3) → sudan II (3118-97-6)

Guidance literature:

With tert.-butylnitrite; In dichloromethane; at 20 ℃; for 24h; Green chemistry;

DOI:10.1177/1747519820964182

Reference yield:

→ Solvent Yellow 14 (3118-97-6)

Guidance literature:

Reference yield:

1-(2,4-dimethylphenylazo)-2-aminonaphthalene (52458-03-4) → sudan II (3118-97-6)

Guidance literature:

With acetic acid; sodium nitrite; Kochen des Reaktionsprodukts mit alkoh.Kalilauge;

upstream raw materials:

methanol

ethanol

1-(2,4-dimethylphenylazo)-2-aminonaphthalene

m-xylene

Downstream raw materials:

C₁₈H₁₆N₂O*C₄₂H₇₀O₃₅

bis-1-(2,4-xylylazo)-2-naphtholate copper(II)

Refernces

• 1、 Akwi, Faith M.,Watts, Paul. "The in situ generation and reactive quench of diazonium compounds in the synthesis of azo compounds in microreactors". . p. 1987 - 2004. Retrieved 2016/10/05.
• 2、 -. "Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator". . . Retrieved 2008/06/13.