Technology Process of Dihydrokawain
There total 30 articles about Dihydrokawain which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 80 percent / sodium borohydride / methanol / 0 - 20 °C
2.1: 46 percent / lipase PS-C / diisopropyl ether / 18 h
3.1: 90 percent / potassium carbonate / methanol
4.1: lithium diisopropylamide / tetrahydrofuran / -78 °C
4.2: tetrahydrofuran / -78 °C
5.1: TFA / CH2Cl2 / 10 h
6.1: potassium carbonate / acetone
With
sodium tetrahydroborate; potassium carbonate; trifluoroacetic acid; lithium diisopropyl amide;
Lipase PS-C;
In
tetrahydrofuran; methanol; dichloromethane; di-isopropyl ether; acetone;
DOI:10.1016/j.tetlet.2006.09.155