5-bromo-2-furamide

Base Information

• Chemical Name: 5-bromo-2-furamide
• CAS No.: 6134-61-8
• Molecular Formula: C5H4 Br N O2
• Molecular Weight: 189.996
• Hs Code.: 2932190090
• Mol file: 6134-61-8.mol

Synonyms:2-Furamide,5-bromo- (7CI,8CI); 5-Bromo-2-furancarboxamide; NSC 32222

Chemical Property of 5-bromo-2-furamide

Chemical Property:

• Vapor Pressure: 0.00966mmHg at 25°C
• Boiling Point: 264.5°C at 760 mmHg
• Flash Point: 113.8°C
• PSA: 56.23000
• Density: 1.773g/cm³
• LogP: 1.84130

Purity/Quality:

97% ^*data from raw suppliers

5-bromo-2-furamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-bromo-2-furamide

There total 5 articles about 5-bromo-2-furamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-bromo-furan-2-carboxylic acid (585-70-6) → 5-bromo-furan-2-carboxylic acid amide (6134-61-8)

Guidance literature:

With N-hydroxybenzotriazole ammonium salt; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

DOI:10.1039/c4gc00853g

Reference yield:

5-bromofuran-2-carbonyl chloride (26726-16-9) → 5-bromo-furan-2-carboxylic acid amide (6134-61-8)

Guidance literature:

With ammonium hydroxide;

DOI:10.1021/ja01106a025

Reference yield:

→ 5-bromo-furan-2-carboxylic acid amide (6134-61-8)

Guidance literature:

With ammonium hydroxide; at 100 ℃; im Druckrohr;

upstream raw materials:

5-bromofuran-2-carbonyl chloride

5-bromo-furan-2-carboxylic acid

Downstream raw materials:

5-(4-chlorophenyl)furan-2-carboxamide

acetic acid 2-(6-tert-butyl-8-fluoro-1-oxo-1H-phthalazin-2-yl)-6-(5-carbamoyl-furan-2-yl)-benzyl ester

5-bromofuran-2-carbonitrile

Refernces

• 1、 -. "IMIDAZO [1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS". Paragraph 00694. . Retrieved 2017/11/04.
• 2、 -. "BENZIMIDAZOLE CANNABINOID AGONISTS BEARING A SUBSTITUTED HETEROCYCLIC GROUP". Paragraph 0174; 0175. . Retrieved 2014/01/07.