2',4'-Dinitroacetanilide

Base Information

• Chemical Name: 2',4'-Dinitroacetanilide
• CAS No.: 610-53-7
• Molecular Formula: C8H7 N3 O5
• Molecular Weight: 225.161
• Hs Code.: 2924299090
• European Community (EC) Number: 210-227-9
• NSC Number: 36974
• DSSTox Substance ID: DTXSID8060587
• Nikkaji Number: J38.251E
• Wikidata: Q72472429
• Mol file: 610-53-7.mol

Synonyms:2,4-Dinitroacetanilide;2',4'-Dinitroacetanilide;610-53-7;N-(2,4-Dinitrophenyl)acetamide;1-Acetamido-2,4-dinitrobenzene;Acetanilide, 2',4'-dinitro-;Acetamide, N-(2,4-dinitrophenyl)-;EINECS 210-227-9;NSC 36974;AI3-17682;NSC36974;Bio8E3;2,4-Dinitro acetanilide;Maybridge1_007736;Acetamide,4-dinitrophenyl)-;SCHEMBL4835079;DTXSID8060587;HMS563H14;N-(2,4-Dinitro-phenyl)-acetamide;N-(2,4-Dinitrophenyl)acetamide #;NSC-36974;AKOS001592843;FT-0632545

Chemical Property of 2',4'-Dinitroacetanilide

Chemical Property:

• Boiling Point: 458.3oC at 760 mmHg
• Flash Point: 231oC
• PSA: 120.74000
• Density: 1.54g/cm3
• LogP: 2.58080
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 225.03857033
• Heavy Atom Count: 16
• Complexity: 308

Purity/Quality:

99.9% ^*data from raw suppliers

2',4'-DINITROACETANILIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-]

Technology Process of 2',4'-Dinitroacetanilide

There total 28 articles about 2',4'-Dinitroacetanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

acetic anhydride (108-24-7) + 2,4-Dinitroanilin (97-02-9) → 2,4-dinitroacetanilide (610-53-7)

Guidance literature:

indium(III) chloride; at 20 ℃; for 0.5h;

DOI:10.1016/S0040-4039(03)01641-1

Reference yield: 98.0%

acetic anhydride (108-24-7) + aniline (62-53-3) → 2,4-dinitroacetanilide (610-53-7)

Guidance literature:

With cupric nitrate trihydrate supported on K 10 montmorillonite clay; nitric acid; In tetrachloromethane; for 2.5h; Ambient temperature;

DOI:10.1021/jo00116a034

Reference yield: 97.0%

N-(4-Nitrophenyl)acetamide (104-04-1) → 2,4-dinitroacetanilide (610-53-7)

Guidance literature:

With ammonium molybdate; water; nitric acid; In chloroform; for 6h; Heating;

DOI:10.1246/cl.2000.48

upstream raw materials:

N-acetyl-N-phenylacetamide

hydroxyimino-acetic acid-(2,4-dinitro-anilide)

acetic anhydride

2,4-Dinitroanilin

Downstream raw materials:

2,4-Dinitroanilin

2-methyl-5-nitrobenzimidazole

4-nitro-2-aminoacetanilide

acetic acid-(2,4-diamino-anilide)

Refernces

• 1、 Venter, Jana,Perez, Concepción,van Otterlo, Willem A.L.,Martínez, Ana,Blackie, Margaret A.L.. "1-Aryl-3-(4-methoxybenzyl)ureas as potentially irreversible glycogen synthase kinase 3 inhibitors: Synthesis and biological evaluation". . p. 1597 - 1600. Retrieved 2019/05/02.
• 2、 Chutia, Rituparna,Chetia, Bolin. "Biogenic CuFe2O4 magnetic nanoparticles as a green, reusable and excellent nanocatalyst for acetylation reactions under solvent-free conditions". . p. 15200 - 15206. Retrieved 2018/09/29.