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Pyridin-2-yl-(3-trifluoromethyl-phenyl)-acetonitrile

Base Information Edit
  • Chemical Name:Pyridin-2-yl-(3-trifluoromethyl-phenyl)-acetonitrile
  • CAS No.:122376-69-6
  • Molecular Formula:C14H9F3N2
  • Molecular Weight:262.234
  • Hs Code.:
  • Mol file:122376-69-6.mol
Pyridin-2-yl-(3-trifluoromethyl-phenyl)-acetonitrile

Synonyms:Pyridin-2-yl-(3-trifluoromethyl-phenyl)-acetonitrile

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Chemical Property of Pyridin-2-yl-(3-trifluoromethyl-phenyl)-acetonitrile Edit
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Technology Process of Pyridin-2-yl-(3-trifluoromethyl-phenyl)-acetonitrile

There total 3 articles about Pyridin-2-yl-(3-trifluoromethyl-phenyl)-acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With potassium tert-butylate; palladium diacetate; nixantphos; In 1,4-dioxane; at 60 ℃; for 10h; Inert atmosphere; Sealed tube;
DOI:10.1016/j.tetlet.2020.152534
Guidance literature:
3-trifluoromethylphenylacetonitrile; With potassium hydroxide; In dimethyl sulfoxide; at 60 ℃;
2-bromo-pyridine; In dimethyl sulfoxide; at 60 - 70 ℃; for 4h;
DOI:10.1016/j.bioorg.2020.103717
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