Technology Process of Propanamide, N-(3,4-dichlorophenyl)-N-(2-(dimethylamino)cyclopentyl)-, cis-
There total 10 articles about Propanamide, N-(3,4-dichlorophenyl)-N-(2-(dimethylamino)cyclopentyl)-, cis- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: concd. HCl / 168 h / Heating
2: 72 h / Heating
3: 85percent aq. ethanolic KOH / 3 h / Ambient temperature
4: CrO3, aq. H2SO4 / acetone / 0.5 h / Ambient temperature
5: 4.2 g / dimethylamine hydrochloride, NaCNBH3 / methanol / 192 h / Ambient temperature
With
chromium(VI) oxide; hydrogenchloride; potassium hydroxide; sulfuric acid; N,N-dimethylammonium chloride; sodium cyanoborohydride;
In
methanol; acetone;
DOI:10.1021/jm00142a020
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 90 percent / H2O
2: 1.) NaH / 1.) THF, reflux, 1 h
3: 2.) 20percent NaOH / 1.) reflux, 17 h, 2.) 1 h
4: Heating
With
sodium hydroxide; sodium hydride;
In
water;
DOI:10.1021/jm00142a020
- Guidance literature:
-
Multi-step reaction with 2 steps
1: CrO3, aq. H2SO4 / acetone / 0.5 h / Ambient temperature
2: 4.2 g / dimethylamine hydrochloride, NaCNBH3 / methanol / 192 h / Ambient temperature
With
chromium(VI) oxide; sulfuric acid; N,N-dimethylammonium chloride; sodium cyanoborohydride;
In
methanol; acetone;
DOI:10.1021/jm00142a020
