(1r,2s,5r)-2-Isopropyl-5-methylcyclohexanamine

Base Information Edit

Chemical Name:(1r,2s,5r)-2-Isopropyl-5-methylcyclohexanamine
CAS No.:2216-54-8
Molecular Formula:C10H21 N
Molecular Weight:155.283
Hs Code.:2921300090
European Community (EC) Number:218-693-5
NSC Number:7325
Nikkaji Number:J96.097G
Mol file:2216-54-8.mol

Synonyms:2216-54-8;(1r,2s,5r)-2-isopropyl-5-methylcyclohexanamine;L-Menthylamine;(1R,2S,5R)-5-Methyl-2-(Propan-2-Yl)Cyclohexan-1-Amine;[1R-(1alpha,2Beta,5alpha)]-2-(isopropyl)-5-methylcyclohexylamine;NSC7325;(-)-Menthylamin;(?)-Menthyl amine;(1R-(1alpha,2beta,5alpha))-2-(Isopropyl)-5-methylcyclohexylamine;SCHEMBL2628606;(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-amine;Cyclohexanamine, 5-methyl-2-(1-methylethyl)-, (1R-(1alpha,2beta,5alpha))-;NSC-7325;AKOS006346010;(5R)-2-isopropyl-5-methylcyclohexanamine;BB 0260182;EN300-393176;J-501618;p-Menthan-3-amine, hydrochloride, (1R,3R,4S)-(-)-;(1R,2S,5R)-2-ISOPROPYL-5-METHYLCYCLOHEXAN-1-AMINE;(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanamine, AldrichCPR;66609-74-3

Suppliers and Price of (1r,2s,5r)-2-Isopropyl-5-methylcyclohexanamine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 8 raw suppliers

Chemical Property of (1r,2s,5r)-2-Isopropyl-5-methylcyclohexanamine Edit

Chemical Property:

Boiling Point:192.8 °C at 760 mmHg
PKA:10.68±0.70(Predicted)
Flash Point:45.8 °C
PSA：26.02000
Density:0.834 g/cm³
LogP:3.10620
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:155.167399674
Heavy Atom Count:11
Complexity:120

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC(C(C1)N)C(C)C
Isomeric SMILES:C[C@@H]1CC[C@H]([C@@H](C1)N)C(C)C

Technology Process of (1r,2s,5r)-2-Isopropyl-5-methylcyclohexanamine

There total 30 articles about (1r,2s,5r)-2-Isopropyl-5-methylcyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 65620-72-6,165874-36-2
(1R,5S)-menthone oxime

: 2216-54-8,787534-09-2
L-menthylamine

Guidance literature:: With ethanol; sodium; In toluene; for 1.5h; Inert atmosphere; Reflux;
DOI:10.1021/acsmedchemlett.1c00001

Reference yield: 98.0%

: 490-99-3,491-01-0,491-02-1,1490-04-6,2216-51-5,2216-52-6,3623-51-6,3623-52-7,3623-53-8,15356-60-2,15356-70-4,20747-49-3,20752-33-4,20752-34-5,23283-97-8,64282-88-8,89-78-1
DL-neomenthol

: 2216-54-8,4894-99-9,7231-40-5,16934-77-3,20706-69-8,20706-70-1,21411-81-4,23399-21-5,51743-63-6,66609-74-3,85549-06-0,787534-09-2
rac-menthylamine

Guidance literature:: DL-neomenthol; With 1-methyl-1H-imidazole; methanesulfonyl chloride; triethylamine; In toluene; at 20 ℃; for 2h;

With sodium azide; In N,N-dimethyl-formamide; at 40 ℃; for 48h;

With hydrogen; nickel; In tetrahydrofuran; at 20 ℃; for 72h;
DOI:10.1002/ejoc.201301566