S-2-(N,N-diisopropylamino)ethyl (4'-chlorobenzoyl)thioformohydroximate

Base Information

• Chemical Name: S-2-(N,N-diisopropylamino)ethyl (4'-chlorobenzoyl)thioformohydroximate
• CAS No.: 102941-55-9
• Molecular Formula: C₁₆H₂₃ClN₂O₂S
• Molecular Weight: 342.89
• Mol file: 102941-55-9.mol

Synonyms:S-2-(N,N-diisopropylamino)ethyl (4'-chlorobenzoyl)thioformohydroximate

Chemical Property of S-2-(N,N-diisopropylamino)ethyl (4'-chlorobenzoyl)thioformohydroximate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of S-2-(N,N-diisopropylamino)ethyl (4'-chlorobenzoyl)thioformohydroximate

There total 3 articles about S-2-(N,N-diisopropylamino)ethyl (4'-chlorobenzoyl)thioformohydroximate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-<<2-(N,N-diisopropylamino)ethyl>thio>-4'-chloroacetophenone (102976-78-3) → S-2-(N,N-diisopropylamino)ethyl (4'-chlorobenzoyl)thioformohydroximate (102941-55-9)

Guidance literature:

With i-propyl nitrite; sodium t-butanolate; In tert-butyl alcohol; at 0 ℃; for 1h;

DOI:10.1021/jm00159a021

Reference yield:

4-chlorobenzoylmethyl bromide (536-38-9) → S-2-(N,N-diisopropylamino)ethyl (4'-chlorobenzoyl)thioformohydroximate (102941-55-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaH / 1.) ether, 0 deg C, 2.) ether, RT, 1h

2: t-BuONa, isopropyl nitrite / 2-methyl-propan-2-ol / 1 h / 0 °C

With i-propyl nitrite; sodium hydride; sodium t-butanolate; In tert-butyl alcohol;

DOI:10.1021/jm00159a021

Reference yield:

2-(diisopropylamino)ethanethiol (5842-07-9) → S-2-(N,N-diisopropylamino)ethyl (4'-chlorobenzoyl)thioformohydroximate (102941-55-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaH / 1.) ether, 0 deg C, 2.) ether, RT, 1h

2: t-BuONa, isopropyl nitrite / 2-methyl-propan-2-ol / 1 h / 0 °C

With i-propyl nitrite; sodium hydride; sodium t-butanolate; In tert-butyl alcohol;

DOI:10.1021/jm00159a021

upstream raw materials:

2-<<2-(N,N-diisopropylamino)ethyl>thio>-4'-chloroacetophenone

4-chlorobenzoylmethyl bromide

2-(diisopropylamino)ethanethiol

Refernces