H-DAB(Z)-OME HCL

Base Information

• Chemical Name: H-DAB(Z)-OME HCL
• CAS No.: 10270-79-8
• Molecular Formula: C₁₃H₁₈N₂O₄*ClH
• Molecular Weight: 302.758
• Mol file: 10270-79-8.mol

Synonyms:N-GAMMA-CARBOBENZOXY-L-2,4-DIAMINOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE;H-DAB(Z)-OME HCL

Chemical Property of H-DAB(Z)-OME HCL

Chemical Property:

• PSA: 94.14000
• LogP: 2.50990

Purity/Quality:

98%,99%, ^*data from raw suppliers

H-L-Dab(Z)-OMe*HCl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-DAB(Z)-OME HCL

There total 1 articles about H-DAB(Z)-OME HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2-Amino-4-benzyloxycarbonylamino-butyric acid (2130-77-0) → H-L-dab(Z)-OMe*HCl (10270-79-8)

Guidance literature:

With hydrogenchloride;

Reference yield:

H-L-dab(Z)-OMe*HCl (10270-79-8) → Formyl-L-leucyl-N4-Z-L-2,4-diamino-butyryl-N4-Z-L-2,4-diamino-buttersaeure

Guidance literature:

Multi-step reaction with 3 steps

1: (i) Et₃N, DMF, (ii) /BRN= 1724154/, DCC

2: aq. NaOH / dioxane

3: (i) ClCO₂Et, Et₃N, THF, dioxane, (ii) /BRN= 2565708/, aq. NaOH

With sodium hydroxide; In 1,4-dioxane;

DOI:10.1002/hlca.19600430136

Reference yield:

H-L-dab(Z)-OMe*HCl (10270-79-8) → Formyl-L-leucyl-Nγ-Z-L-α,γ-diamino-buttersaeure-hydrazid

Guidance literature:

Multi-step reaction with 2 steps

1: (i) Et₃N, DMF, (ii) /BRN= 1724154/, DCC

2: N₂H₄*H₂O / methanol

With hydrazine hydrate; In methanol;

DOI:10.1002/hlca.19600430136

upstream raw materials:

(S)-2-Amino-4-benzyloxycarbonylamino-butyric acid

Downstream raw materials:

(S)-2-benzoylamino-4-benzyloxycarbonylamino-butyric acid methyl ester

N^α-tert.-Butyloxycarbonyl-N^γ-benzyloxycarbonyl-L-diaminobutyryl-N^γ-benzyloxycarbonyl-L-diaminobuttersaeuremethylester

N^α,N^γ-Di-Z-L-α,γ-Dab-N^γ-Z-L-α,γ-Dab-OMe