4-Bromophenacylamine hydrochloride

Base Information Edit

Chemical Name:4-Bromophenacylamine hydrochloride
CAS No.:5467-72-1
Molecular Formula:C8H9BrClNO
Molecular Weight:250.523
Hs Code.:29223900
European Community (EC) Number:226-778-3
NSC Number:25405
ChEMBL ID:CHEMBL1801613
Mol file:5467-72-1.mol

Synonyms:5467-72-1;4-Bromophenacylamine hydrochloride;2-Amino-4'-bromoacetophenone hydrochloride;2-amino-1-(4-bromophenyl)ethanone Hydrochloride;2-Amino-4'-bromoacetophenone HCl;Ethanone, 2-amino-1-(4-bromophenyl)-, hydrochloride;2-Amino-1-(4-bromophenyl)ethanone, HCl;MFCD00051998;2-Amino-1-(4-bromophenyl)ethanone HCl;2-Amino-4'-Bromoacetophenone hydrochloride;CHEMBL1801613;C8H8BrNO.ClH;2-AMINO-4-BROMOACETOPHENONE HYDROCHLORIDE;SCHEMBL203985;2-Amino-1-(4-bromophenyl)-1-ethanone hydrochloride;C8-H8-Br-N-O.Cl-H;4-Bromophenacylaminehydrochloride;p-bromophenacylamine hydrochloride;ROAVTVXTYFSQEA-UHFFFAOYSA-N;AMY10368;BCP24959;NSC25405;CCG-45828;NSC-25405;AKOS005069361;CS-W009051;AC-24722;SY028321;2-Amino-1-(4-bromo-phenyl)-ethanone HCl;|A-AMino-4'-broMoacetophenone hydrochloride;FT-0617908;2-Amino-1-(4-bromo-phenyl)-ethanone HCl salt;amino-(4'bromo) acetophenone hydrochloride salt;EN300-235700;amino-(4' bromo) acetophenone hydrochloride salt;2-Amino-4'-bromoacetophenone hydrochloride, 96%;2-AMINO-4'-BROMOACETOPHENONE?HYDROCHLORIDE;A830316;10Z-0719;2-Amino-1-(4-bromo-phenyl)-ethanone hydrochloride;2-AMINO-4\'-BROMOACETOPHENONE HYDROCHLORIDE;SR-01000635574-1;2-amino-1-(4-bromo-phenyl)ethan-1-one hydrochloride;2-amino-1-(4-bromophenyl)ethanone hydrochloride salt;Z1741980207;2-amino-1-(4-bromo-phenyl)-ethanone hydrochloric acid salt;2-Amino-4 inverted exclamation mark -bromoacetophenone Hydrochloride

Suppliers and Price of 4-Bromophenacylamine hydrochloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-4′-bromoacetophenone hydrochloride
25g
$ 275.00

TRC
2-Amino-4′-bromoacetophenone hydrochloride
250mg
$ 45.00

TCI Chemical
2-Amino-4'-bromoacetophenone Hydrochloride >98.0%(HPLC)(N)
1g
$ 19.00

TCI Chemical
2-Amino-4'-bromoacetophenone Hydrochloride >98.0%(HPLC)(N)
5g
$ 71.00

SynQuest Laboratories
4-Bromophenacylamine hydrochloride
5 g
$ 152.00

SynQuest Laboratories
4-Bromophenacylamine hydrochloride
250 mg
$ 32.00

SynQuest Laboratories
4-Bromophenacylamine hydrochloride
1 g
$ 68.00

Sigma-Aldrich
2-Amino-4′-bromoacetophenone hydrochloride 96%
1g
$ 20.20

Sigma-Aldrich
2-Amino-4′-bromoacetophenone hydrochloride 96%
5g
$ 90.00

Medical Isotopes, Inc.
4-BromophenacylamineHCl 98%
1 g
$ 335.00

Total 75 raw suppliers

Chemical Property of 4-Bromophenacylamine hydrochloride Edit

Chemical Property:

Vapor Pressure:0.000272mmHg at 25°C
Melting Point:285 °C (dec.)(lit.)
Refractive Index:1.589
Boiling Point:322.8 °C at 760 mmHg
Flash Point:149 °C
PSA：43.09000
Density:1.52g/cm³
LogP:3.09280
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:248.95560
Heavy Atom Count:12
Complexity:141

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Amino-4′-bromoacetophenone hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)CN)Br.Cl
Uses 2-Amino-4''-bromoacetophenone Hydrochloride is used as a reagent in the synthesis of Ledipasvir (L320100); a potent, once-daily oral NS5A inhibitor used for treatment of hepatitis C virus infection. 2-Amino-4''-bromoacetophenone Hydrochloride is also used in the preparation of the β-receptor agonists (-)-Denopamine (D231485) and (-)-Arbutamine (A766300).

Technology Process of 4-Bromophenacylamine hydrochloride

There total 9 articles about 4-Bromophenacylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 127118-88-1
C₁₀H₈BrNO₃

: 5467-72-1
α-amino-4-bromoacetophenone hydrochloride

Guidance literature:: With hydrogenchloride; ethanol; for 48h; Ambient temperature;
DOI:10.1055/s-1990-26959

Reference yield: 92.0%

: 99-73-0,132309-76-3
para-bromophenacyl bromide

: 5467-72-1
α-amino-4-bromoacetophenone hydrochloride

Guidance literature:: para-bromophenacyl bromide; With hexamethylenetetramine; In toluene; at 40 ℃; for 16h;

With hydrogenchloride; water; In toluene; at 20 ℃; for 20h;