PF-3758309

Base Information

• Chemical Name: PF-3758309
• CAS No.: 898044-15-0
• Molecular Formula: C25H30N8OS
• Molecular Weight: 490.62
• Mol file: 898044-15-0.mol

Synonyms:X4Z;PF-309;CS-1014;PF-3758309;PF-03758309;PF 3758309;PF3758309;PF-3758309 USP/EP/BP;PF-03758309/PF03758309;p21-Activated Kinase Inhibitor II, PF-3758309 - CAS 898044-15-0 - Calbiochem;N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl

Chemical Property of PF-3758309

Chemical Property:

• PKA: 12.82±0.40(Predicted)
• PSA: 137.03000
• Density: 1.325±0.06 g/cm3(Predicted)
• LogP: 4.09380
• Storage Temp.: -20C
• Solubility.: ≥24.53 mg/mL in DMSO; insoluble in H2O; ≥101.4 mg/mL in EtOH with gentle warming and ultrasonic

Purity/Quality:

97% ^*data from raw suppliers

p21-Activated Kinase Inhibitor II, PF-3758309 - CAS 898044-15-0 - Calbiochemp21-Activated Kinase Inhibitor II, PF-3758309, CAS 898044-15-0, is a cell-permeable, reversible, potent inhibitor of p21-activated kinases (IC50 = 190 and 99 nM against PAK1 and PAK3, respectively). ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: PF-3758309 is a pyrrolopyrazole inhibitor of PAK4 (p21-activated kinase). It is used in biological studies for targeting Rho GTPase signaling for cancer therapy.