7,9-dihydro-1H-purine-6,8-dione

Base Information

• Chemical Name: 7,9-dihydro-1H-purine-6,8-dione
• CAS No.: 13231-00-0
• Molecular Formula: C5H4 N4 O2
• Molecular Weight: 152.112
• Hs Code.: 2933990090
• Mol file: 13231-00-0.mol

Synonyms:6,8-Purinediol(3CI); Purine-6,8(1H,9H)-dione (6CI,7CI,8CI); 6,8-Dihydroxypurine; NSC 23164;Purine-6,8-dione

Chemical Property of 7,9-dihydro-1H-purine-6,8-dione

Chemical Property:

• Vapor Pressure: 2.21E-14mmHg at 25°C
• Boiling Point: 587.1°Cat760mmHg
• Flash Point: 308.9°C
• PSA: 94.92000
• Density: 2.19g/cm³
• LogP: -0.23590
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

7H-Purine-6,8-diol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7,9-dihydro-1H-purine-6,8-dione

There total 17 articles about 7,9-dihydro-1H-purine-6,8-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

hypoxanthine 7-N-oxide (118974-81-5) → diceto-6,8 purine (13231-00-0)

Guidance literature:

With acetic acid; at 95 - 100 ℃; for 20h;

DOI:10.1248/cpb.40.612

Reference yield: 7.0%

hypoxanthine (68-94-0) → diceto-6,8 purine (13231-00-0) + xanthine (69-89-6)

Guidance literature:

With water; for 48h; Irradiation;

Reference yield: 4.0%

adenine 7-oxide (21149-25-7) → diceto-6,8 purine (13231-00-0) + hypoxanthine 7-N-oxide (118974-81-5)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; at 90 ℃;

upstream raw materials:

phosgene

5,6-diamino-3H-pyrimidin-4-one; sulfate

5,6-diamino-4(3H)-pyrimidinone

urea

Downstream raw materials:

7(9)H-purine-6,8-diyldiamine

8-chloroadenine

8-chloro-1,7-dihydro-purine-6-thione

8-chlorohypoxanthine

Refernces

• 1、 Kawashima,Kumashiro. "-". . p. 750. Retrieved 1969.
• 2、 Fujii, Tozo,Ogawa, Kazuo,Saito, Tohru,Kobayashi, Keiko,Itaya, Taisuke. "SYNTHESIS OF ADENINE 7-OXIDE FROM ADENINE: UTILIZATION OF A BENZYL GROUP AS A CONTROL SYNTHON AT THE 3-POSITION". . p. 477 - 480. Retrieved 2007/10/02.
• 3、 Ogawa, Kazuo,Saito, Tohru,Nohara, Fujio,Nishii, Masahiro,Itaya, Taisuke,Fujii, Tozo. "SYNTHESIS OF HYPOXANTHINE 7-OXIDE, A NEW N-OXIDE AT THE 6-OXOPURINE LEVEL". . p. 885 - 888. Retrieved 2007/10/02.