Technology Process of Eupatilin
There total 16 articles about Eupatilin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
scandium tris(trifluoromethanesulfonate);
In
1,2-dichloro-ethane;
for 24h;
Reagent/catalyst;
Reflux;
Sealed tube;
- Guidance literature:
-
With
hydrogenchloride; aluminium trichloride;
In
chloroform; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 9 steps
1: potassium carbonate / acetone / 60 °C
3: potassium hydroxide; pyridine / diethylene glycol; water / 100 °C
4: pyridine; dipotassium peroxodisulfate; tetraethylammonium hydroxide / water / 24 h / 20 °C
5: acetone / 5 h / Reflux
6: potassium hydroxide / ethanol / 20 °C
7: selenium(IV) oxide / i-Amyl alcohol / Reflux
8: hydrogen; palladium 10% on activated carbon / chloroform / 20 °C
9: aluminum (III) chloride / acetonitrile / 1.5 h / Reflux
With
pyridine; selenium(IV) oxide; aluminum (III) chloride; dipotassium peroxodisulfate; palladium 10% on activated carbon; hydrogen; tetraethylammonium hydroxide; potassium carbonate; potassium hydroxide;
In
ethanol; i-Amyl alcohol; chloroform; water; acetone; acetonitrile; diethylene glycol;
