Trimethylsilyl trimethylsilylcarbamate

Base Information

• Chemical Name: Trimethylsilyl trimethylsilylcarbamate
• CAS No.: 35342-88-2
• Molecular Formula: C7H19 N O2 Si2
• Molecular Weight: 205.404
• Hs Code.: 2931900090
• European Community (EC) Number: 252-520-4
• DSSTox Substance ID: DTXSID60188838
• Nikkaji Number: J260.594E
• Wikidata: Q83060689
• Mol file: 35342-88-2.mol

Synonyms:35342-88-2;N,O-Bis(trimethylsilyl)carbamate;Trimethylsilyl trimethylsilylcarbamate;trimethylsilyl N-trimethylsilylcarbamate;EINECS 252-520-4;Carbamic acid, (trimethylsilyl)-, trimethylsilyl ester;Trimethylsilyl N-(trimethylsilyl)carbamate;C7H19NO2Si2;SCHEMBL2942237;C7-H19-N-O2-Si2;DTXSID60188838;DGIJAZGPLFOQJE-UHFFFAOYSA-N;MFCD00040476;Trimethylsilyl-N-trimethylsilylcarbamate;BSC;FT-0757486;(Trimethylsilyl)carbamic acid trimethylsilyl ester;N,O-Bis(trimethylsilyl)carbamate, >=98.0% (T)

Chemical Property of Trimethylsilyl trimethylsilylcarbamate

Chemical Property:

• Melting Point: 71-80 °C(lit.)
• Boiling Point: 77 °C
• Flash Point: °C
• PSA: 38.33000
• Density: 0.901g/cm³
• LogP: 2.77330
• Storage Temp.: -20°C
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 205.09543192
• Heavy Atom Count: 12
• Complexity: 169

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,O-Bis(trimethylsilyl)carbamate ≥98.0% (T) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](C)(C)NC(=O)O[Si](C)(C)C
• Recent ClinicalTrials: Effects of CPAP on Cognitive Function, Neurocognitive Architecture and Function in Patients With OSA: The SMOSAT Trial

Technology Process of Trimethylsilyl trimethylsilylcarbamate

There total 21 articles about Trimethylsilyl trimethylsilylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.1%

ammonium carbamate (1111-78-0) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → N,O-bis<(trimethylsilyl)oxy>acetamide (35342-88-2)

Guidance literature:

With sulfuric acid; In chloroform; at 35 - 40 ℃; for 15h;

Reference yield: 85.0%

carbon dioxide (124-38-9,18923-20-1) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → N,O-bis<(trimethylsilyl)oxy>acetamide (35342-88-2) + trimethylsilyl allylcarbamate (51041-96-4)

Guidance literature:

With (chloromethyl)methoxydimethylsilane; 1-amino-2-propene; at 45 - 47 ℃; for 10h;

DOI:10.1007/BF00703492

Reference yield: 85.0%

3,5-dimethyl-1H-pyrazole (67-51-6) + carbon dioxide (124-38-9,18923-20-1) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → N,O-bis<(trimethylsilyl)oxy>acetamide (35342-88-2) + 3,5-dimethyl-1-(trimethylsilyl)-1H-pyrazole (18290-96-5)

Guidance literature:

at 50 - 55 ℃; for 20h;

DOI:10.1134/S1070363211070140

upstream raw materials:

chloro-trimethyl-silane

ammonium carbamate

trimethylsilyl carbamate

carbon dioxide

Downstream raw materials:

N-(2,6-dimethylphenyl)-N-trimethylsilylamine

2,6-dimethyl-N-(trimethylsiloxycarbonyl)aniline

N-trimethylsilylaniline

N-(trimethylsilyl)carbamatobenzene

Refernces

• 1、 Sommer,P.,Birkofer,L.. "-". . p. C1 - C4. Retrieved 1975.
• 2、 Lebedev,Lebedeva,Sheludyakov,Ovcharuk,Kovaleva,Ustinova. "Organosilicon synthesis of isocyanates: III. Synthesis of aliphatic, carbocyclic, aromatic, and alkylaromatic isocyanatocatboxylic acid esters". . p. 1069 - 1080. Retrieved 2008/02/05.
• 3、 Kirilin, A. D.,Sokova, N. B.,Chernyshev, E. A.. "The reaction of chloromethylsilanes with amines, hexamethyldisilazanes, and silylcarbamates". . p. 1703 - 1706. Retrieved 2007/10/02.